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Proteins/UNIPROT:P49918
Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Function from UniProtKB (P49918), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 rows
79 statements
79 statements · 4 reference databases · Subject: CDKN1C · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: CDKN1C