Proteins/UNIPROT:A2VDJ0

TMEM131L

ProteinUNIPROT:A2VDJ0

[Isoform 1]: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation..

Function from UniProtKB (A2VDJ0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

19 statements

19 statements · 2 reference databases · Subject: TMEM131L · Sources: gene ontology, Hetionet

Order

TMEM131L covaries with DCHS2ProteinHetionet hetionet:covaries:23240-54798Inferred only
TMEM131L covaries with GALNT15ProteinHetionet hetionet:covaries:117248-23240Inferred only
TMEM131L covaries with ZIC5ProteinHetionet hetionet:covaries:23240-85416Inferred only
TMEM131L regulates negative regulation of canonical Wnt signaling pathwayBiological processgene ontology A2VDJ0|GO:0090090Inferred only
TMEM131L regulates negative regulation of immature T cell proliferation in thymusBiological processgene ontology A2VDJ0|GO:0033088Inferred only
TMEM131L decreases the expression of ARNT2ProteinHetionet hetionet:regulates:23240-9915Inferred only
ASCC3 decreases the expression of TMEM131LProteinHetionet hetionet:regulates:10973-23240Inferred only
FBXL12 decreases the expression of TMEM131LProteinHetionet hetionet:regulates:54850-23240Inferred only
TMEM131L decreases the expression of FKBP4ProteinHetionet hetionet:regulates:23240-2288Inferred only
GLI1 increases the expression of TMEM131LProteinHetionet hetionet:regulates:2735-23240Inferred only
TMEM131L increases the expression of MALProteinHetionet hetionet:regulates:23240-4118Inferred only
NME1 increases the expression of TMEM131LProteinHetionet hetionet:regulates:4830-23240Inferred only

Show the remaining 7

TMEM131L decreases the expression of OSBPL10ProteinHetionet hetionet:regulates:23240-114884Inferred only
POLA2 decreases the expression of TMEM131LProteinHetionet hetionet:regulates:23649-23240Inferred only
TMEM131L decreases the expression of PTPROProteinHetionet hetionet:regulates:23240-5800Inferred only
TMEM131L increases the expression of RPL39LProteinHetionet hetionet:regulates:23240-116832Inferred only
TMEM131L decreases the expression of RPS4Y1ProteinHetionet hetionet:regulates:23240-6192Inferred only
SETDB1 increases the expression of TMEM131LProteinHetionet hetionet:regulates:9869-23240Inferred only
TMEM131L decreases the expression of SUPV3L1ProteinHetionet hetionet:regulates:23240-6832Inferred only

Other names

2 names

Resolves to: TMEM131L

Also called: KIAA0922Transmembrane protein 131-like

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