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Proteins/UNIPROT:P49641
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Function from UniProtKB (P49641), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
83 statements
83 statements · 4 reference databases · Subject: MAN2A2 · Sources: Hetionet, Reactome, UniProt, WikiPathways
2 reactions
2water+MAM02598g2D-mannose+MAM02597g
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.114Golgi apparatus
Human-GEM MAR07324CC BY 4.0Reference data
N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+2water2CHEBI:28729+an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]
5 names
Resolves to: MAN2A2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:56052CC BY 4.0Reference data