O-4,8-dimethylnonanoyl-(R)-carnitine

Three steps

• isobutyryl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrixOne of 3 routes

• 3-methylbut-2-enoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. glycine-N-acyltransferase (3-methylcrotonoylglycine)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 2 moreperoxisome, cytosol, mitochondrial matrix

• isovaleryl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. glycine N-acyltransferase (isovalerylglycine)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrixOne of 3 routes

• arachidonoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Arachidonate:CoA ligase (AMP-forming)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 9 moreperoxisome, cytosolOne of 14 routes

• CHEBI:15519Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. propanoyl-CoA C-acyltransferase

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosolOne of 2 routes

• palmitoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Palmitate:CoA ligase (AMP-forming)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 9 moreperoxisome, cytosolOne of 18 routes

• oleoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Transport of octadecenoyl-CoA into Mitochondrial Matrix

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 1 moreperoxisome, cytosolOne of 14 routes

• phenylacetyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Phenylacetate:CoA ligase

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 1 moreperoxisome, cytosolOne of 3 routes

• L-leucineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and leucine (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• 12(S)-HPETEReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. arachidonate:oxygen 12-oxidoreductase

  Catalysed by CRAT, CROT, ALOX12peroxisome, endoplasmic reticulum, cytosolOne of 4 routes

• 15(S)-HPETEReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. arachidonate:oxygen 15-oxidoreductase

  Catalysed by CRAT, CROT, ALOX15B, ALOX15peroxisome, endoplasmic reticulum, cytosolOne of 4 routes

• 5(S)-HPETEReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. Arachidonate:oxygen 5-oxidoreductase

  Catalysed by CRAT, CROT, ALOX5peroxisome, endoplasmic reticulum, cytosol

• CHEBI:15650Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. N-acetyl-LTE4 to leukotriene E4 conversion

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 33 moreperoxisome, cytosolOne of 2 routes

• CHEBI:15727Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 2 moreperoxisome, cytosol

• CHEBI:15746Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. diamine N-acetyltransferase (N1-acetylspermine)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 3 moreperoxisome, cytosolOne of 2 routes

• CHEBI:15971Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and histidine (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosol

• sulfateReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and sulfate (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14, SLC26A6peroxisome, extracellular space, cytosol

• 11-cis-retinolReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Palmitoyl-CoA:retinol O-acyltransferase

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 6 moreperoxisome, cytosol

• (R)-carnitineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. solute carrier (L-carnitine)
  3. O-octanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-octanoyl-(R)-carnitine(out) + (R)-carnitine(in)

  Catalysed by CRAT, CROT, SLC25A20peroxisome, mitochondrial matrix, cytosol, inner side of the membrane, outer side of the membraneOne of 8 routes

• iodideReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and iodide (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14, SLC26A4peroxisome, extracellular space, cytosol

• L-valineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and valine (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• oxaloacetateReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. ATP citrate lyase (citrate)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 2 moreperoxisome, cytosol

• L-arginineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of arginine and chloride (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• CHEBI:16856Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. transport of arachidonate and GSH (cytosol to extracellular)

  Catalysed by CRAT, CROTperoxisome, endoplasmic reticulum, cytosol, extracellular spaceOne of 2 routes

• CHEBI:16857Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. Transport of L-Threonine by Atb0 Transporter

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosol

• oxalic acidReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and oxalate (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14, SLC26A6peroxisome, extracellular space, cytosol

• L-isoleucineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and isoleucine (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• CHEBI:17203Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. Transport of L-Proline by the Apical Imino Amino Acid Transporters

  Catalysed by CRAT, CROT, SLC6A14, CLTRN and 1 moreperoxisome, extracellular space, cytosolOne of 2 routes

• anilineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Acetyl-CoA:arylamine N-acetyltransferase

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 3 moreperoxisome, cytosol

• CHEBI:17312Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. N1,N12-diacetylspermine to N1-acetylspermine conversion

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 1 moreperoxisome, cytosolOne of 2 routes

• L-cysteineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. N-acetylglutamate synthase (N-acetyl-L-cysteine)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 2 moreperoxisome, cytosol, mitochondrial matrixOne of 3 routes

• hexadecanalReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. 2 H+[c] + NADH[c] + palmitate[c] = H2O[c] + hexadecanal[c] + NAD+[c]

  Catalysed by CRAT, CROT, ALDH3B1, ALDH3B2 and 1 moreperoxisome, endoplasmic reticulum, cytosolOne of 2 routes

• (7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrix

• glycine betaineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of betaine and chloride (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14, SLC6A12peroxisome, extracellular space, cytosolOne of 3 routes

• CHEBI:17895Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. Transport of L-Tyrosine by Atb0 Transporter

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• CHEBI:17927Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. N1,N8-diacetylspermidine to N1-acetylspermidine conversion

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 1 moreperoxisome, cytosol

• butanoateReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. transport of butyryl-CoA and L-carnitine (cytosol to mitochondria)
  3. butanoyl-CoA + H2O = butanoate + CoA + H(+)

  Catalysed by CRAT, CROT, SLC33A1, ESCO2 and 7 moreperoxisome, mitochondrial matrix, cytosol

• CHEBI:18019Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of chloride and lysine (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosol

• L-glutamineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. Transport of L-Glutamine by Atb0 Transporter

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosol

• CHEBI:18095Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. transport of trans-4-hydroxy-L-proline (cytosol to extracellular)

  Catalysed by CRAT, CROT, SLC6A14, CLTRN and 1 moreperoxisome, extracellular space, cytosol

• N-carbamoyl-beta-alanineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine Transport by Atb0
  3. Transport of 3-Ureidopropionate

  Catalysed by CRAT, CROT, SLC6A14peroxisome, extracellular space, cytosolOne of 2 routes

• 1-butanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. transport of butyryl-CoA and L-carnitine (cytosol to mitochondria)
  3. 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA = 1-butanoyl-2-(9Z-octadecenoyl)-glycerol + CoA

  Catalysed by CRAT, CROT, SLC33A1, ESCO2 and 3 moreperoxisome, mitochondrial matrix, cytosol

• O-butanoyl-(R)-carnitineReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. transport of butyryl-CoA and L-carnitine (cytosol to mitochondria)
  3. butanoyl-CoA + (R)-carnitine = O-butanoyl-(R)-carnitine + CoA

  Catalysed by CRAT, CROT, SLC33A1, ESCO2 and 1 moreperoxisome, mitochondrial matrix, cytosol

• (5Z)-dodecenoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxomyrist-7-enoyl-CoA)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrixOne of 2 routes

• O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronateReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Utilized Transport
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronate + UDP

  Catalysed by CRAT, CROT, UGT1A9, UGT2B7 and 4 moreperoxisome, endoplasmic reticulum, cytosol

• (11Z)-docosenoyl-CoA(4-)Reach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. long-chain-fatty-acid-CoA ligase (cis-cetoleic acid)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 9 moreperoxisome, cytosolOne of 5 routes

• (7Z)-tetradecenoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. long-chain-fatty-acid-CoA ligase ((7Z)-tetradecenoic acid)

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 9 moreperoxisome, cytosolOne of 8 routes

• (4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Fatty Acid Beta Oxidation (C18:4->C16:4), Mitochondrial

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrixOne of 3 routes

• (7Z,10Z)-hexadecadienoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Fatty Acid Beta Oxidation Trans (C18:2->C16:2), Mitochondrial

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrix

• (4Z,7Z)-decadienoyl-CoAReach from here →
  1. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
  2. Carnitine O-Palmitoyltransferase
  3. Fatty Acid Beta Oxidation (C12:3->C10:2), Mitochondrial

  Catalysed by CRAT, CROT, CPT1A, CPT1C and 4 moreperoxisome, cytosol, mitochondrial matrixOne of 2 routes