(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

696 compounds within 3 steps: 11 in 1, 171 in 2, 514 in 3

Three steps

N-(9Z-hexadecenoyl)-glycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes
8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoateReach from here →
1. Beta Oxidation of Long Chain Fatty Acid
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ECI2, ACADL, HADHA, ECI1 and 8 moremitochondrial matrix, cytosol
11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoateReach from here →
1. Beta Oxidation of Long Chain Fatty Acid
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ECI2, ACADL, HADHA, ECI1 and 9 moremitochondrial matrix, cytosol
14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoateReach from here →
1. Beta Oxidation of Long Chain Fatty Acid
2. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ECI2, ACADL, HADHA, ECI1 and 9 moremitochondrial matrix, cytosol
2-hydroxyoctanoyl-CoAReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. octanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctanoyl-CoA + succinate + CO2
Catalysed by BAAT, ACOT6, CROT, PHYHcytosol, mitochondrial matrix
2-hydroxydecanoyl-CoAReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. medium-chain acyl-CoA ligase (decanoic acid)
3. decanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydecanoyl-CoA + succinate + CO2
Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 5 morecytosol
2-hydroxyeicosanoyl-CoAReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
2-hydroxydodecanoyl-CoAReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydodecanoyl-CoA + succinate + CO2
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
2-hydroxytetradecanoyl-CoAReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxytetradecanoyl-CoA + succinate + CO2
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
11-cis-retinyl tetradecanoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes
9-cis-retinyl tetradecanoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
13-cis-retinyl tetradecanoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 13-cis-retinol + tetradecanoyl-CoA = 13-cis-retinyl tetradecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
all-trans-retinyl tetradecanoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. all-trans-retinol + tetradecanoyl-CoA = all-trans-retinyl tetradecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
tetradecyl tetradecanoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecan-1-ol + tetradecanoyl-CoA = tetradecyl tetradecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
(7S,17S)-dihydroperoxy-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate
3. (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S,17S)-dihydroperoxy-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoate
Catalysed by BAAT, ACOT6, ALOX5, ALOX15B and 2 morecytosol
N-hexadecanoylglycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix
N-dodecanoylglycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes
N-decanoylglycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. medium-chain acyl-CoA ligase (decanoic acid)
3. decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)
Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 5 morecytosolOne of 2 routes
N-octanoylglycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
Catalysed by BAAT, ACOT6, CROT, GLYATL2cytosol, mitochondrial matrixOne of 2 routes
N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. 5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix
L-cystine-bis-glycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 3 morecytosol, mitochondrial matrix
sn-glycero-3-phosphoethanolamineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
2. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
3. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by LPCAT1, PLA2G15, PLA2G4C
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol
a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol
a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol
a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 1 morecytosol
an N-octadecanoyl-sphingoid baseReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosol
glycyldehydrophenylalanineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix
an N-(fatty acyl)-glycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 1 morecytosol, mitochondrial matrix
1-(10Z-heptadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(10Z-heptadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
N-(9Z,12Z-octadecadienoyl)-glycineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosolOne of 2 routes
cholesteryl (7Z)-octadecenoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
3. (7Z)-octadecenoyl-CoA + cholesterol = cholesteryl (7Z)-octadecenoate + CoA
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 2 morecytosol
acetylcholineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. Acetyl-CoA:choline O-acetyltransferase
Catalysed by BAAT, ACOT6, CHATcytosol, nucleusOne of 3 routes
pyruvateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
3. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
Catalysed by BAAT, ACOT6, AGXT2cytosol, mitochondrial matrixOne of 20 routes
CHEBI:15467Reach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Acetoacetate:CoA ligase (AMP-forming)
3. 3-hydroxy-3-methylglutaryl-CoA synthase (acetoacetyl-CoA)
Catalysed by BAAT, ACOT6, AACS, HMGCS1cytosolOne of 3 routes
CHEBI:15570Reach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. transport of D-alanine and glycine (cytosol to extracellular)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 3 morecytosol, mitochondrial matrix, extracellular spaceOne of 3 routes
(S)-malateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. ATP citrate lyase (citrate)
3. transport of malate and OAA (cytosol to mitochondria)
Catalysed by BAAT, ACOT6, ACLYcytosol, mitochondrial matrixOne of 5 routes
L-leucineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. transport of glycine and leucine (cytosol to extracellular)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix, extracellular spaceOne of 21 routes
(7S,14S)-dihydroperoxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoateReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate
3. (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S,14S)-dihydroperoxy-(4Z,8E,10Z,12E,16Z,19Z)-docosahexaenoate
Catalysed by BAAT, ACOT6, ALOX5, ALOX15 and 1 morecytosol
CHEBI:15611Reach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. S-Adenosyl-L-methionine:glycine N-methyltransferase
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix
CHEBI:15699Reach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. transport of glycine and homoserine (cytosol to extracellular)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix, extracellular spaceOne of 17 routes
betaine aldehydeReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Acetyl-CoA:choline O-acetyltransferase
3. choline dehydrogenase (choline)
Catalysed by BAAT, ACOT6, CHAT, CHDHcytosol, nucleusOne of 4 routes
trimethylenediamineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. diamine N-acetyltransferase (N1-acetylspermidine)
3. deoxyhypusine synthase (1,3-diaminopropane)
Catalysed by BAAT, ACOT6, SAT1, SAT2 and 1 morecytosolOne of 2 routes
hexadecanoic acidReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase
3. Utilized Transport
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosol, endoplasmic reticulumOne of 16 routes
1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. Acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase
3. plasmenylethanolamine 2-acylhydrolase
Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 18 morecytosol
CHEBI:15971Reach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. transport of glycine and histidine (cytosol to extracellular)
Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 2 morecytosol, mitochondrial matrix, extracellular spaceOne of 11 routes
11-cis-retinalReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Palmitoyl-CoA:retinol O-acyltransferase
3. 11-cis-retinol:NAD+ oxidoreductase
Catalysed by BAAT, ACOT6, DGAT1, LRAT and 10 morecytosolOne of 4 routes
cholesterolReach from here →
1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + cholesterol = a cholesterol ester + CoA
3. a cholesterol ester + H2O = cholesterol + a fatty acid + H(+)
Catalysed by SOAT2, SOAT1, CES1, LIPN and 2 morecytosol
hexadecan-1-olReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Palmitate:CoA ligase (AMP-forming)
3. formate dehydrogenase (palmitoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol, peroxisome
L-cystineReach from here →
1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
3. Transport of L-Cystine (L-Alanine antiport) by B0, +At Transporter
Catalysed by BAAT, ACOT6, SLC7A9, SLC3A1cytosol, mitochondrial matrix, extracellular spaceOne of 5 routes