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Proteins/UNIPROT:Q5VXI9
Plays a highly specific role in the last step of keratinocyte differentiation. Contains two distinct domains: the alpha/beta hydrolase fold and the abhydrolase-associated lipase region, also features the consensus sequence of the active site of a genuine lipase. May have an essential function in lipid metabolism of the most differentiated epidermal layers..
Function from UniProtKB (Q5VXI9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
10 statements
10 statements · 3 reference databases · Subject: LIPN · Sources: Hetionet, Reactome, Rhea
4 reactions
a sterol ester+watera sterol+a fatty acid+hydron
Catalysed by CEL or LIPA or LIPN
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10100CC BY 4.0Reference data
a triacylglycerol+watera diacylglycerol+a fatty acid+hydron
Catalysed by
2 names
Resolves to: LIPN
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12044CC BY 4.0Reference data
a triacylglycerol+watera 1,2-diacylglycerol+a fatty acid+hydron
Catalysed by LIPA or PNPLA4 or LIPN or PNPLA2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:35667CC BY 4.0Reference data
a cholesterol ester+watercholesterol+a fatty acid+hydron
Catalysed by CES1 or LIPN or NCEH1 or LDAH
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36403CC BY 4.0Reference data