glutathione

Three steps

• (3S)-citramalyl-CoAReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. 3-mercaptopyruvate:sulfide sulfurtransferase
  3. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA

  Catalysed by TSTD1, MPST, TST, CLYBLcytosol

• an S-substituted L-cysteineReach from here →
  1. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)
  2. an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
  3. an S-substituted L-cysteinylglycine + H2O = an S-substituted L-cysteine + glycine

  Catalysed by GSTT4, GSTA4, GSTZ1, LANCL1 and 25 more

• 5-amino-2-oxopentanoateReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. 3-mercaptopyruvate:sulfide sulfurtransferase
  3. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine

  Catalysed by TSTD1, MPST, TST, AGXT2cytosol

• deoxycholoyl-CoAReach from here →
  1. glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)
  2. Glycodeoxycholate amidohydrolase
  3. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)

  Catalysed by ABCC4, SLC27A2, SLC27A5inner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

• hyodeoxycholateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of lithocholate (cytosol to extracellular)
  3. cytochrome P450 (lithocholate)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 3 moreextracellular space, cytosol

• N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosolOne of 3 routes

• N-[(R)-4-phosphopantothenoyl]-L-cysteineReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
  3. (R)-4'-phosphopantothenate:L-cysteine ligase

  Catalysed by TSTD1, CBS, PPCScytosolOne of 4 routes

• (6R)-L-erythro-5,6,7,8-tetrahydrobiopterinReach from here →
  1. urate(out) + glutathione(in) = urate(in) + glutathione(out)
  2. urate(out) + a dicarboxylate(in) = urate(in) + a dicarboxylate(out)
  3. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)

  Catalysed by SLC22A13, SLC22A6, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

• (2S)-2-phospholactateReach from here →
  1. urate(out) + glutathione(in) = urate(in) + glutathione(out)
  2. urate(out) + (S)-lactate(in) = urate(in) + (S)-lactate(out)
  3. (2S)-2-phospholactate + H2O = (S)-lactate + phosphate

  Catalysed by SLC22A13, SLC22A12, PGPinner side of the membrane, outer side of the membraneOne of 2 routes

• a 2,3-dehydroacyl-CoAReach from here →
  1. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O
  2. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O
  3. a 2,3-saturated acyl-CoA + A = a 2,3-dehydroacyl-CoA + AH2

  Catalysed by PTGES, MGST3, GPX1, GPX2 and 4 more

• heme bReach from here →
  1. L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate
  2. Fe(3+)(out) + L-ascorbate(in) = monodehydro-L-ascorbate radical(in) + Fe(2+)(out) + H(+)
  3. Ferrochelatase, Mitochondrial

  Catalysed by CLIC1, GSTO1, GSTO2, CYB561D2 and 5 moreinner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 3 routes

• N-benzoylglycineReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. Hippurate (Benzoylglycinate) Formation

  Catalysed by MGST3, GSTM4, LTC4S, MGST2cytosol, mitochondrial matrixOne of 4 routes

• 3-sulfino-L-alanineReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
  3. L-Cysteine:oxygen oxidoreductase

  Catalysed by TSTD1, CBS, CDO1cytosolOne of 2 routes

• Fe(II)-heme aReach from here →
  1. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O
  2. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O
  3. Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2

  Catalysed by PTGES, MGST3, GPX1, GPX2 and 4 more

• (4R)-4-hydroxy-2-oxoglutarateReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. 3-mercaptopyruvate:sulfide sulfurtransferase
  3. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

  Catalysed by TSTD1, MPST, TST, HOGA1cytosol

• (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylateReach from here →
  1. a quinone + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + a quinol
  2. a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)
  3. trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)

  Catalysed by SQOR, CYC1, UQCRFS1, PRODH2outer side of the membraneOne of 2 routes

• (5-hydroxyindol-3-yl)acetateReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. sulfite:ferricytochrome-c oxidoreductase
  3. Transport of 5-Hydroxyindoleacetate

  Catalysed by TSTD1, SUOX, SLC4A1mitochondrial matrix, cytosol, extracellular spaceOne of 2 routes

• chenodeoxycholoyl-CoAReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. solute carrier organic anion transporter (chenodiol)
  3. chenodeoxycholate + ATP + CoA = chenodeoxycholoyl-CoA + AMP + diphosphate

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 3 moreextracellular space, cytosol

• 18-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. cytochrome P450 (arachidonate)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol, endoplasmic reticulumOne of 2 routes

• Mo-molybdopterinReach from here →
  1. glutathione + H2O = L-cysteinylglycine + L-glutamate
  2. gamma-glutamyltransferase (alanine)
  3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

  Catalysed by GGT3P, GGT1, GGT5, GGT6 and 4 morecytosolOne of 2 routes

• (R)-adrenalineReach from here →
  1. L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate
  2. dopamine + 2 L-ascorbate + O2 = (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O
  3. (R)-noradrenaline + S-adenosyl-L-methionine = (R)-adrenaline + S-adenosyl-L-homocysteine + H(+)

  Catalysed by CLIC1, GSTO1, GSTO2, DBH and 1 more

• (4S)-4-hydroxy-2-oxoglutarateReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. 3-mercaptopyruvate:sulfide sulfurtransferase
  3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

  Catalysed by TSTD1, MPST, TST, HOGA1cytosol

• CHEBI:742324Reach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of dopamine (cytosol to extracellular)
  3. S-Adenosyl-L-methionine:catechol O-methyltransferase

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 4 moreextracellular space, cytosol

• (2S)-2-aminobutanoateReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosolOne of 2 routes

• (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. Arachidonate:oxygen 8-oxidoreductase

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosolOne of 2 routes

• 2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerolReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. fatty acid amide hydrolase (arachidonate)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• NAADP(+)Reach from here →
  1. urate(out) + glutathione(in) = urate(in) + glutathione(out)
  2. nicotinate(in) + urate(out) = nicotinate(out) + urate(in)
  3. nicotinate + NADP(+) = NAADP(+) + nicotinamide

  Catalysed by SLC22A13, SLC22A12, CD38inner side of the membrane, outer side of the membraneOne of 2 routes

• 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 6 moreextracellular space, cytosol

• 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
  3. 10-HETE[n] + NAD+[n] = H+[n] + NADH[n] + 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate[n]

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol, nucleusOne of 3 routes

• 7-oxolithocholateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. solute carrier organic anion transporter (chenodiol)
  3. chenodeoxycholate + NAD(+) = 7-oxolithocholate + NADH + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 3 moreextracellular space, cytosolOne of 2 routes

• (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosolOne of 2 routes

• (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosolOne of 2 routes

• (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. Arachidonate: oxygen 11-oxidoreductase

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosolOne of 2 routes

• thio-Mo-molybdopterinReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
  3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

  Catalysed by TSTD1, CBS, MOCOScytosol

• 17beta-estradiol 17-O-(beta-D-glucuronate)Reach from here →
  1. glycocholate(in) + glutathione(in) + ATP + H2O = glycocholate(out) + glutathione(out) + ADP + phosphate + H(+)
  2. glycocholate(out) + glutarate(in) = glycocholate(in) + glutarate(out)
  3. 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)

  Catalysed by ABCC4, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes

• 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. unspecific monooxygenase (arachidonate)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 28 moreextracellular space, cytosolOne of 4 routes

• 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. unspecific monooxygenase (arachidonate)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 27 moreextracellular space, cytosolOne of 3 routes

• 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserineReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of arachidonate (cytosol to extracellular)
  3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol

• 11beta-prostaglandin F2Reach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of prostaglandin D2 (cytosol to extracellular)
  3. prostaglandin D2 + NADPH + H(+) = 11beta-prostaglandin F2 + NADP(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 3 moreextracellular space, cytosol

• a methyl thioetherReach from here →
  1. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
  2. L-cysteinyl-[sulfatase] + 2 a thiol + O2 = an organic disulfide + 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + H2O + H(+)
  3. a thiol + S-adenosyl-L-methionine = a methyl thioether + S-adenosyl-L-homocysteine + H(+)

  Catalysed by TSTD1, SUMF1, TMT1B, TMT1A

• N-tetradecanoylglycineReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosolOne of 3 routes

• N-eicosanoylglycinateReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosol

• N-docosanoylglycineReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosol

• N-hexacosanoylglycineReach from here →
  1. leukotriene C4 = leukotriene A4 + glutathione
  2. leukotriene C4 hydrolysis
  3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

  Catalysed by MGST3, GSTM4, LTC4S, MGST2 and 1 morecytosol

• 16alpha-hydroxydehydroepiandrosterone 3-sulfateReach from here →
  1. 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)
  2. transport of dehydroepiandrosterone sulfate (cytosol to extracellular)
  3. dehydroepiandrosterone 3-sulfate + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxydehydroepiandrosterone 3-sulfate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PTGES, LANCL1, GSTM4, MGST2 and 2 moreextracellular space, cytosol