Compound
7-oxolithocholate
A bile acid anion that is the conjugate base of 7-oxolithocholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:78605), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C24H37O4
- Mass
- 389.556 g/mol
- Charge
- -1
- InChIKey
- DXOCDBGWDZAYRQ-AURDAFMXSA-M
- SMILES
- [H][C@]12CC(=O)[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(=O)[O-])[C@@]1(C)CC[C@@H](O)C2
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: 7-oxolithocholate · Sources: Rhea
- 7-oxolithocholate is converted to chenodeoxycholateCompoundRhea RHEA:53820Inferred only
- chenodeoxycholate is converted to 7-oxolithocholateCompoundRhea RHEA:42036Inferred only
- 7-oxolithocholate is converted to ursodeoxycholateCompoundRhea RHEA:47540Inferred only
- ursodeoxycholate is converted to 7-oxolithocholateCompoundRhea RHEA:42028Inferred only
- 7-oxolithocholate is a substrate of HSD11B1ProteinRhea RHEA:47540Inferred only
- 7-oxolithocholate is a substrate of HSD11B1ProteinRhea RHEA:53820Inferred only
Reactions
4 reactions
ursodeoxycholate+NAD(1-)7-oxolithocholate+NADH(2-)+hydron
Catalysed by HSD17B10
Reaction pageLeft to rightBalanced
Rhea RHEA:42028CC BY 4.0Reference data
chenodeoxycholate+NAD(1-)7-oxolithocholate+NADH(2-)+hydron
Catalysed by HSD17B10
Reaction pageLeft to rightBalanced
Rhea RHEA:42036CC BY 4.0Reference data
7-oxolithocholate+NADPH(4-)+hydronursodeoxycholate+NADP(3-)
Catalysed by HSD11B1
Reaction pageLeft to rightBalanced
Rhea RHEA:47540CC BY 4.0Reference data
chenodeoxycholate+NADP(3-)7-oxolithocholate+NADPH(4-)+hydron
Catalysed by HSD11B1
Reaction pageRight to leftBalanced
Rhea RHEA:53820CC BY 4.0Reference data
Other names
6 names
Resolves to: 7-oxolithocholate
- Also called
- 3alpha-hydroxy-7-oxo-5beta-cholan-24-oate7-ketolithocholate7-oxo-3alpha-hydroxy-5beta-cholan-24-oate7-oxo-3α-hydroxy-5β-cholan-24-oate
- Systematic name
- (3alpha,5beta)-3-hydroxy-7-oxocholan-24-oate(3α,5β)-3-hydroxy-7-oxocholan-24-oate