Compound

hyodeoxycholate

A bile acid anion that is the conjugate base of hyodeoxycholic acid.

Definition from ChEBI (CHEBI:58875), read 2026-09-23. CC BY 4.0.

CHEBI:58875ChEBI

Open in the graph

Structure

2D depiction · 3D model shown

Loading the model…

A generated conformer of hyodeoxycholate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C24H39O4
Mass: 391.572 g/mol
Charge: -1
InChIKey: DGABKXLVXPYZII-SIBKNCMHSA-M
SMILES: [H][C@@]12C[C@H](O)[C@]3([H])C[C@H](O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@H](C)CCC(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

22 statements

22 statements · 2 reference databases · Subject: hyodeoxycholate · Sources: Human-GEM, Rhea

Order

hyodeoxycholate is converted to hyodeoxycholate 6-O-(beta-D-glucuronate)CompoundRhea RHEA:52964Inferred only
hyodeoxycholate is converted to hyodeoxycholoyl-24-O-(beta-D-glucuronate)CompoundRhea RHEA:52956Inferred only
lithocholic acid is converted to hyodeoxycholateCompoundHuman-GEM MAR01838Inferred only
hyodeoxycholate is metabolised by UGT1A3ProteinHuman-GEM MAR12255Inferred only
hyodeoxycholate is metabolised by UGT1A3ProteinRhea RHEA:52956Inferred only
hyodeoxycholate is metabolised by UGT1A3ProteinHuman-GEM MAR12254Inferred only
hyodeoxycholate is metabolised by UGT2A1ProteinHuman-GEM MAR12259Inferred only
hyodeoxycholate is metabolised by UGT2A1ProteinHuman-GEM MAR12255Inferred only
hyodeoxycholate is metabolised by UGT2A1ProteinHuman-GEM MAR12254Inferred only
hyodeoxycholate is metabolised by UGT2A1ProteinHuman-GEM MAR12258Inferred only
hyodeoxycholate is metabolised by UGT2A1ProteinRhea RHEA:52956Inferred only
hyodeoxycholate is metabolised by UGT2A2ProteinRhea RHEA:52964Inferred only

Show the remaining 10

hyodeoxycholate is metabolised by UGT2A3ProteinRhea RHEA:52964Inferred only
hyodeoxycholate is metabolised by UGT2A3ProteinHuman-GEM MAR12259Inferred only
hyodeoxycholate is metabolised by UGT2A3ProteinHuman-GEM MAR12255Inferred only
hyodeoxycholate is metabolised by UGT2A3ProteinHuman-GEM MAR12258Inferred only
hyodeoxycholate is metabolised by UGT2A3ProteinHuman-GEM MAR12254Inferred only
hyodeoxycholate is metabolised by UGT2B4ProteinHuman-GEM MAR12259Inferred only
hyodeoxycholate is metabolised by UGT2B4ProteinHuman-GEM MAR12258Inferred only
hyodeoxycholate is metabolised by UGT2B7ProteinHuman-GEM MAR12259Inferred only
hyodeoxycholate is metabolised by UGT2B7ProteinRhea RHEA:52964Inferred only
hyodeoxycholate is metabolised by UGT2B7ProteinHuman-GEM MAR12258Inferred only

Reactions

13 reactions

2proton+lithocholic acid+NADPH(4-)+dioxygenwater+hyodeoxycholate+NADP(3-)
Catalysed by CYP3A4
Reaction pageLeft to rightBalancedEC 1.14.14.57cytosol
Human-GEM MAR01838CC BY 4.0Reference data
hyodeoxycholatehyodeoxycholate
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR09188CC BY 4.0Reference data
hyodeoxycholate
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09462CC BY 4.0Reference data
ATP+CHEBI:1146900+hyodeoxycholateAMP+proton+diphosphate(3-)+MAM10040c
Reaction pageLeft to rightBalancedEC 6.2.1.7cytosol
Human-GEM MAR10121CC BY 4.0Reference data
water+MAM10040cCHEBI:1146900+hyodeoxycholate
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR10122CC BY 4.0Reference data
hyodeoxycholate+UDP-alpha-D-glucuronateproton+UDP+MAM03644c
Catalysed by UGT2A3 or UGT2A1 or UGT1A3
Reaction pageLeft to rightBalancedEC 2.4.1.17cytosol
Human-GEM MAR12254CC BY 4.0Reference data
hyodeoxycholate+UDP-alpha-D-glucuronateproton+UDP+MAM03644r
Catalysed by UGT2A3 or UGT2A1 or UGT1A3
Reaction pageLeft to rightBalancedEC 2.4.1.17endoplasmic reticulum
Human-GEM MAR12255CC BY 4.0Reference data
hyodeoxycholate+UDP-alpha-D-glucuronateproton+UDP+MAM03645c
Catalysed by UGT2A3 or UGT2B4 or UGT2B7 or UGT2A1
Reaction pageLeft to rightBalancedEC 2.4.1.17cytosol
Human-GEM MAR12258CC BY 4.0Reference data
hyodeoxycholate+UDP-alpha-D-glucuronateproton+UDP+MAM03645r
Catalysed by UGT2A3 or UGT2B4 or UGT2B7 or UGT2A1
Reaction pageLeft to rightBalancedEC 2.4.1.17endoplasmic reticulum
Human-GEM MAR12259CC BY 4.0Reference data
hyodeoxycholatehyodeoxycholate
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR12283CC BY 4.0Reference data
lithocholate+reduced [NADPH--hemoprotein reductase]+dioxygenhyodeoxycholate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23644CC BY 4.0Reference data
hyodeoxycholate+UDP-alpha-D-glucuronatehyodeoxycholoyl-24-O-(beta-D-glucuronate)+UDP
Catalysed by UGT2A1 or UGT1A3
Reaction pageLeft to rightBalanced
Rhea RHEA:52956CC BY 4.0Reference data

Show the remaining 1

Other names

4 names

Resolves to: hyodeoxycholate

Also called: (3alpha,5beta,6alpha)-3,6-dihydroxycholan-24-oate(3α,5β,6α)-3,6-dihydroxycholan-24-oate
Systematic name: 3alpha,6alpha-dihydroxy-5beta-cholan-24-oate3α,6α-dihydroxy-5β-cholan-24-oate