Compound

(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

A hydroperoxy fatty acid anion that is the conjugate base of 15(R)-HPETE, obtained by deprotonation of the carboxy group; major species at pH 7.3.

Definition from ChEBI (CHEBI:82626), read 2026-09-23. CC BY 4.0.

CHEBI:82626ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C20H31O4
Mass: 335.464 g/mol
Charge: -1
InChIKey: BFWYTORDSFIVKP-UDQWCNDOSA-M
SMILES: CCCCC[C@H](/C=C/C=CC/C=CC/C=CCCCC(=O)[O-])OO
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

PTGS2ProteinUNIPROT:P35354substrate ofInferred only56 paths56 endpoints

What the reference databases state

Chemical structure

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is the enantiomer of (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundChEBI CHEBI:57446Inferred only

Statements

3 statements

3 statements · 1 reference database · Subject: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate · Sources: Rhea

Order

(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to (5Z,8Z,11Z,14Z)-eicosatetraenoateCompoundRhea RHEA:42284Inferred only
(5Z,8Z,11Z,14Z)-eicosatetraenoate is converted to (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:42284Inferred only
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is a substrate of PTGS2ProteinRhea RHEA:42284Inferred only

Reactions

3 reactions

(5Z,8Z,11Z,14Z)-eicosatetraenoate+dioxygen(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by PTGS2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42284CC BY 4.0Reference data
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+water
Catalysed by ALOX15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:50152CC BY 4.0Reference data
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateCHEBI:137324
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:53404CC BY 4.0Reference data

Other names

4 names

Resolves to: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

Also called: (15R)-Hp-(5Z,8Z,11Z,13E)-ETE(15R)-HpETE(5Z,8Z,11Z,13E,15R)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate
Systematic name: (5Z,8Z,11Z,13E,15R)-15-hydroperoxyicosa-5,8,11,13-tetraenoate