Compound

a ganglioside GD1alpha (d18:1(4E))

An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy groups of α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer; major species at pH 7.3.

Definition from ChEBI (CHEBI:78569), read 2026-09-23. CC BY 4.0.

CHEBI:78569ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C67H111N4O39R
Mass: 1596.604 g/mol
Charge: -2
SMILES: *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO[C@]4(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O4)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H]4O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

4 statements

4 statements · 1 reference database · Subject: a ganglioside GD1alpha (d18:1(4E)) · Sources: Rhea

Order

a ganglioside GD1alpha (d18:1(4E)) is a substrate of ST6GALNAC3ProteinRhea RHEA:41968Inferred only
a ganglioside GD1alpha (d18:1(4E)) is a substrate of ST6GALNAC4ProteinRhea RHEA:41968Inferred only
a ganglioside GD1alpha (d18:1(4E)) is a substrate of ST6GALNAC5ProteinRhea RHEA:41968Inferred only
a ganglioside GD1alpha (d18:1(4E)) is a substrate of ST6GALNAC6ProteinRhea RHEA:41968Inferred only

Reactions

2 reactions

a ganglioside GM1b (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GD1alpha (d18:1(4E))+CMP+hydron
Catalysed by ST6GALNAC3 or ST6GALNAC6 or ST6GALNAC5 or ST6GALNAC4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41968CC BY 4.0Reference data
a ganglioside GD1alpha (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GT1aalpha (d18:1(4E))+CMP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79803CC BY 4.0Reference data

Other names

6 names

Resolves to: a ganglioside GD1alpha (d18:1(4E))

Also called: alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-ceramide(2-)alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-alpha-N-acetylneuraminosyl-(2->6)-N-acetyl-beta-D-galactosaminyl-(1->4)- beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-N-acylsphingosine(2-)Ganglioside GD1a alpha (d18:1(4E))GD1a alpha(d18:1(4E))α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-[α-N-acetylneuraminosyl-(2→6)]-N-acetyl-β-D-galactosaminyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide(2−)α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-α-N-acetylneuraminosyl-(2→6)-N-acetyl-β-D-galactosaminyl-(1→4)- β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-N-acylsphingosine(2−)