Compound
a ganglioside GT3 (d18:1(4E))
An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy groups of ganglioside GT3; major species at pH 7.3.
Definition from ChEBI (CHEBI:78438), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C64H104N4O37R
- Mass
- 1521.518 g/mol
- Charge
- -3
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@@H](CO)O[C@]4(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@@H](CO)O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)O4)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
8 statements
8 statements · 2 reference databases · Subject: a ganglioside GT3 (d18:1(4E)) · Sources: Human-GEM, Rhea
- a ganglioside GT3 (d18:1(4E)) is converted to CHEBI:1146900CompoundHuman-GEM MAR08228Inferred only
- a ganglioside GT3 (d18:1(4E)) is converted to CHEBI:1146900CompoundHuman-GEM MAR08227Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of B4GALNT1ProteinHuman-GEM MAR00856Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of B4GALNT1ProteinHuman-GEM MAR08192Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of SLC33A1ProteinHuman-GEM MAR08227Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of SLC33A1ProteinHuman-GEM MAR08228Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of ST8SIA1ProteinRhea RHEA:41764Inferred only
- a ganglioside GT3 (d18:1(4E)) is a substrate of ST8SIA5ProteinRhea RHEA:41764Inferred only
Reactions
9 reactions
CMP-N-acetyl-beta-neuraminate+a ganglioside GD3 (d18:1(4E))cytidine 5'-monophosphate+a ganglioside GT3 (d18:1(4E))+proton
Catalysed by ST8SIA5 or ST8SIA1
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.8, 2.4.99.-GO:0005829
Human-GEM MAR00855CC BY 4.0Reference data
a ganglioside GT3 (d18:1(4E))+MAM03110cMAM02032c+proton+UDP
Catalysed by B4GALNT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.92GO:0005829
Human-GEM MAR00856CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a ganglioside GD3 (d18:1(4E))cytidine 5'-monophosphate+a ganglioside GT3 (d18:1(4E))+proton
Catalysed by ST8SIA5
Reaction pageLeft to rightBalance undeterminableEC 2.4.99.-GO:0005794
Human-GEM MAR08180CC BY 4.0Reference data
a ganglioside GT3 (d18:1(4E))+MAM03110gMAM02032g+proton+UDP
Catalysed by B4GALNT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.92GO:0005794
Human-GEM MAR08192CC BY 4.0Reference data
CHEBI:15351+a ganglioside GT3 (d18:1(4E))MAM01245c+CHEBI:1146900
Catalysed by SLC33A1
Reaction pageLeft to rightBalance undeterminableGO:0005829
Human-GEM MAR08227CC BY 4.0Reference data
CHEBI:15351+a ganglioside GT3 (d18:1(4E))MAM01245g+CHEBI:1146900
Catalysed by SLC33A1
Reaction pageLeft to rightBalance undeterminableGO:0005794
Human-GEM MAR08228CC BY 4.0Reference data
a ganglioside GD3 (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GT3 (d18:1(4E))+CMP+hydron
Catalysed by ST8SIA5 or ST8SIA1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41764CC BY 4.0Reference data
a ganglioside GT3 (d18:1(4E))+UDP-N-acetyl-alpha-D-galactosamineCHEBI:87788+UDP+hydron
Catalysed by B4GALNT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47580CC BY 4.0Reference data
a ganglioside GT3 (d18:1(4E))+acetyl-CoACHEBI:230526+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79763CC BY 4.0Reference data
Other names
10 names
Resolves to: a ganglioside GT3 (d18:1(4E))
- Also called
- alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-ceramide(3-)alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer(3-)alpha-Neup5NAc-(2->8)-alpha-Neup5NAc-(2->8)-alpha-Neup5NAc-(2->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(11')-Cer(3-)Ganglioside GT3 (d18:1(4E))GT3GT3(d18:1(4E))NeuAcalpha2-8NeuAcalpha2-8NeuAcalpha2-3Galbeta1-4Glcbeta-Cerα-N-acetylneuraminosyl-(2→8)-α-N-acetylneuraminosyl-(2→8)-α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide(3−)α-Neu5Ac-(2→8)-α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)-β-Gal-(1→4)-β-Glc-(1→1')-Cer(3−)α-Neup5NAc-(2→8)-α-Neup5NAc-(2→8)-α-Neup5NAc-(2→3)-β-D-Galp-(1→4)-β-D-Glcp-(1↔1')-Cer(3−)