Compound
ganglioside GM2 (d18:1(4E)/18:0)
An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy group of ganglioside GM2 (18:0); major species at pH 7.3.
Definition from ChEBI (CHEBI:78485), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C67H120N3O26
- Mass
- 1383.692 g/mol
- Charge
- -1
- InChIKey
- GIVLTTJNORAZON-HDBOBKCLSA-M
- SMILES
- [H][C@@]1([C@H](O)[C@H](O)CO)O[C@@](O[C@@H]2[C@@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)/C=C/CCCCCCCCCCCCC)O[C@@H]3CO)O[C@H](CO)[C@@H]2O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(C(=O)[O-])C[C@H](O)[C@H]1NC(C)=O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: ganglioside GM2 (d18:1(4E)/18:0) · Sources: Rhea
- ganglioside GM2 (d18:1(4E)/18:0) is a substrate of ST3GAL5ProteinRhea RHEA:41776Inferred only
Reactions
3 reactions
ganglioside GA2 (d18:1(4E)/18:0)+CMP-N-acetyl-beta-neuraminateganglioside GM2 (d18:1(4E)/18:0)+CMP+hydron
Catalysed by ST3GAL5
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41776CC BY 4.0Reference data
ganglioside GM2 (d18:1(4E)/18:0)+waterganglioside GA2 (d18:1(4E)/18:0)+N-acetylneuraminate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:47920CC BY 4.0Reference data
ganglioside GM1 (d18:1(4E)/18:0)+waterganglioside GM2 (d18:1(4E)/18:0)+D-galactose
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48044CC BY 4.0Reference data
Other names
7 names
Resolves to: ganglioside GM2 (d18:1(4E)/18:0)
- Also called
- GM2(d18:1(4E)/18:0)N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-N-octadecanoylsphingosineN-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-N-stearoylsphingosine(1-)N-acetyl-β-D-galactosaminyl-(1→4)-[α-N-acetylneuraminosyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-N-octadecanoylsphingosineN-acetyl-β-D-galactosaminyl-(1→4)-[α-N-acetylneuraminosyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-N-stearoylsphingosine(1−)
- Systematic name
- (2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->4)-[(6R)-5-acetamido-3,5-dideoxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-beta-L-threo-hex-2-ulopyranonosyl-(2->3)]-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside(2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1→4)-[(6R)-5-acetamido-3,5-dideoxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-β-L-threo-hex-2-ulopyranonosyl-(2→3)]-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside