Compound
a ganglioside GT1b
An anionic ganglioside arising from deprotonation of the neuraminosyl carboxy groups of α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-[α-N-acetylneuraminosyl-(2→8)-α-N-acetylneuraminosyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide; major species at pH 7.3.
Definition from ChEBI (CHEBI:82940), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C63H98N5O47R2
- Mass
- 1677.46 g/mol
- Charge
- -3
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@@H](CO)O[C@]4(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O4)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@@H](*)O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: a ganglioside GT1b · Sources: Rhea
- a ganglioside GT1b is a substrate of NEU2ProteinRhea RHEA:47828Inferred only
- a ganglioside GT1b is a substrate of NEU3ProteinRhea RHEA:47828Inferred only
- a ganglioside GT1b is a substrate of ST8SIA6ProteinRhea RHEA:48932Inferred only
Reactions
4 reactions
a ganglioside GT1b+watera ganglioside GD1b+N-acetylneuraminate
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47828CC BY 4.0Reference data
a ganglioside GD1b+CMP-N-acetyl-beta-neuraminatea ganglioside GT1b+CMP+hydron
Catalysed by ST3GAL1 or ST3GAL2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48240CC BY 4.0Reference data
a ganglioside GT1b+CMP-N-acetyl-beta-neuraminatea ganglioside GQ1b+CMP+hydron
Catalysed by ST8SIA6
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48932CC BY 4.0Reference data
a ganglioside GT1b+CMP-N-acetyl-beta-neuraminateCHEBI:141711+CMP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79963CC BY 4.0Reference data
Other names
5 names
Resolves to: a ganglioside GT1b
- Also called
- alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu45Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(11')-Cer(3-)Ganglioside GT1bganglioside GT1b(3-)ganglioside GT1b(3−)α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu45Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer(3−)