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Proteins/UNIPROT:O94892
Homologous recombination repressor that functions as a poly(ADP-ribose) (PAR) reader regulating DNA damage response and PARP inhibition. Once recruited to DNA lesions via DNA-, in a PAR-dependent mechanism, stimulates PARP1 activity. Binds preferentially ssDNA and inhibits EXO1-mediated resection, probably through a PAR-independent DNA-binding mechanism..
Function from UniProtKB (O94892), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
312 statements
312 statements · 3 reference databases · Subject: ZNF432 · Sources: gene ontology, Hetionet, Reactome · Rows fetched: 300
2 names
Resolves to: ZNF432