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Proteins/UNIPROT:Q9NS91
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity..
Function from UniProtKB (Q9NS91), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
42 statements
42 statements · 4 reference databases · Subject: RAD18 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
6 names
Resolves to: RAD18
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data