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Proteins/UNIPROT:Q9BQI6
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions..
Function from UniProtKB (Q9BQI6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
34 statements
34 statements · 3 reference databases · Subject: SLF1 · Sources: gene ontology, Hetionet, WikiPathways
5 names
Resolves to: SLF1