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Proteins/UNIPROT:Q9BS16

CENPK

Protein·UNIPROT:Q9BS16

Open in the graph

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore..

Function from UniProtKB (Q9BS16), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

30 statements

30 statements · 2 reference databases · Subject: CENPK · Sources: Hetionet, Reactome

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CENPK covaries with EPHX3ProteinHetionet hetionet:covaries:64105-79852Inferred only
TIMM23 covaries with CENPKProteinHetionet hetionet:covaries:100287932-64105Inferred only
CENPK covaries with ZNF432ProteinHetionet hetionet:covaries:64105-9668Inferred only
CENPK covaries with ZNF565ProteinHetionet hetionet:covaries:147929-64105Inferred only
CENPK covaries with ZNF570ProteinHetionet hetionet:covaries:148268-64105Inferred only
ZNF793 covaries with CENPKProteinHetionet hetionet:covaries:390927-64105Inferred only
CENPK interacts with PCBD2ProteinHetionet hetionet:interacts:64105-84105Inferred only
SOX6 interacts with CENPKProteinHetionet hetionet:interacts:55553-64105Inferred only
UBC interacts with CENPKProteinHetionet hetionet:interacts:64105-7316Inferred only
CENPK participates in Amplification of signal from unattached kinetochores via a MAD2 inhibitory signalPathwayReactome R-HSA-141444Inferred only
CENPK participates in Amplification of signal from the kinetochoresPathwayReactome R-HSA-141424Inferred only
CENPK participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only

Show the remaining 18

CENPK participates in Cell Cycle CheckpointsPathwayReactome R-HSA-69620Inferred only
CENPK participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
CENPK participates in Chromosome MaintenancePathwayReactome R-HSA-73886Inferred only
CENPK participates in Deposition of new CENPA-containing nucleosomes at the centromerePathwayReactome R-HSA-606279Inferred only
CENPK participates in EML4 and NUDC in mitotic spindle formationPathwayReactome R-HSA-9648025Inferred only
CENPK participates in M PhasePathwayReactome R-HSA-68886Inferred only
CENPK participates in Mitotic AnaphasePathwayReactome R-HSA-68882Inferred only
CENPK participates in Mitotic Metaphase and AnaphasePathwayReactome R-HSA-2555396Inferred only
CENPK participates in Mitotic PrometaphasePathwayReactome R-HSA-68877Inferred only
CENPK participates in Mitotic Spindle CheckpointPathwayReactome R-HSA-69618Inferred only
CENPK participates in Nucleosome assemblyPathwayReactome R-HSA-774815Inferred only
CENPK participates in Resolution of Sister Chromatid CohesionPathwayReactome R-HSA-2500257Inferred only
CENPK participates in RHO GTPase EffectorsPathwayReactome R-HSA-195258Inferred only
CENPK participates in RHO GTPases Activate ForminsPathwayReactome R-HSA-5663220Inferred only
CENPK participates in Separation of Sister ChromatidsPathwayReactome R-HSA-2467813Inferred only
CENPK participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CENPK participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
CENPK participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Other names

6 names

Resolves to: CENPK

Also called: AF-5alphaCENP-KICEN37Interphase centromere complex protein 37p33Protein AF-5alpha

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