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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O94856

NFASC

Protein·UNIPROT:O94856

Open in the graph

Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions..

Function from UniProtKB (O94856), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

neurodevelopmental disorder with central and peripheral motor dysfunction has a germline basis in NFASCDiseaseGenCC HGNC:29866|MONDO:0032698Inferred only

Statements

25 statements

25 statements · 3 reference databases · Subject: NFASC · Sources: Hetionet, Reactome, WikiPathways

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H2BC4; H2BC6; H2BC7; H2BC8; H2BC10 covaries with NFASCProteinHetionet hetionet:covaries:23114-8339Inferred only
HOXC10 covaries with NFASCProteinHetionet hetionet:covaries:23114-3226Inferred only
OR2V2 covaries with NFASCProteinHetionet hetionet:covaries:23114-285659Inferred only
SAMD9 covaries with NFASCProteinHetionet hetionet:covaries:23114-54809Inferred only
ZNF432 covaries with NFASCProteinHetionet hetionet:covaries:23114-9668Inferred only
ANK1 interacts with NFASCProteinHetionet hetionet:interacts:23114-286Inferred only
CNTNAP1 interacts with NFASCProteinHetionet hetionet:interacts:23114-8506Inferred only
DCX interacts with NFASCProteinHetionet hetionet:interacts:1641-23114Inferred only
NRCAM interacts with NFASCProteinHetionet hetionet:interacts:23114-4897Inferred only
SCN1B interacts with NFASCProteinHetionet hetionet:interacts:23114-6324Inferred only
NFASC interacts with SCN3BProteinHetionet hetionet:interacts:23114-55800Inferred only
SCNN1B interacts with NFASCProteinHetionet hetionet:interacts:23114-6338Inferred only

Show the remaining 13

SDCBP interacts with NFASCProteinHetionet hetionet:interacts:23114-6386Inferred only
NFASC interacts with SDCBP2ProteinHetionet hetionet:interacts:23114-27111Inferred only
TNR interacts with NFASCProteinHetionet hetionet:interacts:23114-7143Inferred only
NFASC participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
NFASC participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
NFASC participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
NFASC participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
NFASC participates in Interaction between L1 and AnkyrinsPathwayReactome R-HSA-445095Inferred only
NFASC participates in L1CAM interactionsPathwayReactome R-HSA-373760Inferred only
NFASC participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
NFASC participates in Neurofascin interactionsPathwayReactome R-HSA-447043Inferred only
NFASC participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
NFASC participates in Sodium channel in epilepsyPathwayWikiPathways WP5598Inferred only

Other names

2 names

Resolves to: NFASC

Also called: KIAA0756Neurofascin

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