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Proteins/UNIPROT:Q7LBC6
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity..
Function from UniProtKB (Q7LBC6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
79 statements
79 statements · 7 reference databases · Subject: KDM3B · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Reactome, UniProt, WikiPathways
1 reaction
N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3]+22-oxoglutarate(2-)+2dioxygenL-lysyl(9)-[histone H3]+2formaldehyde+2succinate(2-)+2carbon dioxide
Catalysed by HR or KDM1A or KDM7A or KDM3B or PHF8 or KDM3A
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:60188CC BY 4.0Reference data
8 names
Resolves to: KDM3B