Proteins/UNIPROT:Q9H777

ELAC1

ProteinUNIPROT:Q9H777

Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1..

Function from UniProtKB (Q9H777), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: ELAC1 · Sources: Hetionet, UniProt

Order

ELAC1 covaries with FKBP2ProteinHetionet hetionet:covaries:2286-55520Inferred only
GPC3 covaries with ELAC1ProteinHetionet hetionet:covaries:2719-55520Inferred only
OR2V2 covaries with ELAC1ProteinHetionet hetionet:covaries:285659-55520Inferred only
ZNF432 covaries with ELAC1ProteinHetionet hetionet:covaries:55520-9668Inferred only
ZNF554 covaries with ELAC1ProteinHetionet hetionet:covaries:115196-55520Inferred only
ZNF580 covaries with ELAC1ProteinHetionet hetionet:covaries:51157-55520Inferred only
ZNF662 covaries with ELAC1ProteinHetionet hetionet:covaries:389114-55520Inferred only
ELAC1 requires the cofactor Zn(2+)CompoundUniProt Q9H777Inferred only

Other names

7 names

Resolves to: ELAC1

Also called: D29Deleted in Ma29ElaC homolog protein 1Ribonuclease Z 1RNase Z 1tRNA 3 endonuclease 1tRNase Z 1

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