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Proteins/UNIPROT:Q99697
May play a role in myoblast differentiation. When unphosphorylated, associates with an ELAVL1-containing complex, which stabilizes cyclin mRNA and ensuring cell proliferation. Phosphorylation by AKT2 impairs this association, leading to CCND1 mRNA destabilization and progression towards differentiation..
[Isoform PTX2C]: Involved in the establishment of left-right asymmetry in the developing embryo..
Function from UniProtKB (Q99697), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
9 rows
40 statements
40 statements · 4 reference databases · Subject: PITX2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
9 names
Resolves to: PITX2