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Proteins/UNIPROT:O95405
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization..
Function from UniProtKB (O95405), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
73 statements
73 statements · 2 reference databases · Subject: ZFYVE9 · Sources: Hetionet, WikiPathways
11 names
Resolves to: ZFYVE9