Proteins/UNIPROT:Q0ZGT2

NEXN

ProteinUNIPROT:Q0ZGT2

Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity..

Function from UniProtKB (Q0ZGT2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

dilated cardiomyopathy 1CC has a germline basis in NEXNDiseaseGenCC HGNC:29557|MONDO:0013147Inferred only
familial isolated dilated cardiomyopathy has a germline basis in NEXNDiseaseGenCC HGNC:29557|MONDO:0700335Inferred only

Statements

12 statements

12 statements · 3 reference databases · Subject: NEXN · Sources: gene ontology, Hetionet, WikiPathways

Order

CCNQ covaries with NEXNProteinHetionet hetionet:covaries:91624-92002Inferred only
CENPE covaries with NEXNProteinHetionet hetionet:covaries:1062-91624Inferred only
JMJD1C covaries with NEXNProteinHetionet hetionet:covaries:221037-91624Inferred only
KLLN covaries with NEXNProteinHetionet hetionet:covaries:100144748-91624Inferred only
TNFSF9 covaries with NEXNProteinHetionet hetionet:covaries:8744-91624Inferred only
ZNF432 covaries with NEXNProteinHetionet hetionet:covaries:91624-9668Inferred only
ZNF566 covaries with NEXNProteinHetionet hetionet:covaries:84924-91624Inferred only
ACTA1 interacts with NEXNProteinHetionet hetionet:interacts:58-91624Inferred only
NELL1 interacts with NEXNProteinHetionet hetionet:interacts:4745-91624Inferred only
NEXN participates in VEGFA VEGFR2 signalingPathwayWikiPathways WP3888Inferred only
NEXN regulates regulation of cell migrationBiological processgene ontology Q0ZGT2|GO:0030334Inferred only
NEXN regulates regulation of cytoskeleton organizationBiological processgene ontology Q0ZGT2|GO:0051493Inferred only

Other names

2 names

Resolves to: NEXN

Also called: F-actin-binding proteinNelin

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