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Proteins/UNIPROT:Q86XT9

TMEM219

Protein·UNIPROT:Q86XT9

Open in the graph

Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding..

Function from UniProtKB (Q86XT9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

26 statements

26 statements · 4 reference databases · Subject: TMEM219 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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TMEM219 covaries with ARHGEF19ProteinHetionet hetionet:covaries:124446-128272Inferred only
TMEM219 covaries with CRXProteinHetionet hetionet:covaries:124446-1406Inferred only
TMEM219 covaries with H2BC4; H2BC6; H2BC7; H2BC8; H2BC10ProteinHetionet hetionet:covaries:124446-8339Inferred only
TMEM219 covaries with IRF2BP1ProteinHetionet hetionet:covaries:124446-26145Inferred only
TMEM219 covaries with LRWD1ProteinHetionet hetionet:covaries:124446-222229Inferred only
TMEM219 covaries with PABPC1L2A; PABPC1L2BProteinHetionet hetionet:covaries:124446-340529Inferred only
TMEM219 covaries with PCDHB15ProteinHetionet hetionet:covaries:124446-56121Inferred only
TMEM219 covaries with RNF215ProteinHetionet hetionet:covaries:124446-200312Inferred only
TMEM219 covaries with SHFLProteinHetionet hetionet:covaries:124446-55337Inferred only
TMEM219 covaries with SLC25A53ProteinHetionet hetionet:covaries:124446-401612Inferred only
TMEM219 covaries with UFSP1ProteinHetionet hetionet:covaries:124446-402682Inferred only
TMEM219 covaries with ZNF197ProteinHetionet hetionet:covaries:10168-124446Inferred only

Show the remaining 14

ZNF286A covaries with TMEM219ProteinHetionet hetionet:covaries:124446-57335Inferred only
ZNF331 covaries with TMEM219ProteinHetionet hetionet:covaries:124446-55422Inferred only
TMEM219 covaries with ZNF432ProteinHetionet hetionet:covaries:124446-9668Inferred only
TMEM219 covaries with ZSCAN21ProteinHetionet hetionet:covaries:124446-7589Inferred only
TMEM219 participates in 16p11 2 proximal deletion syndromePathwayWikiPathways WP4949Inferred only
TMEM219 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
TMEM219 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
TMEM219 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
TMEM219 participates in TP53 Regulates Transcription of Cell Death GenesPathwayReactome R-HSA-5633008Inferred only
TMEM219 participates in TP53 Regulates Transcription of Death Receptors and LigandsPathwayReactome R-HSA-6803211Inferred only
TMEM219 participates in Transcriptional Regulation by TP53PathwayReactome R-HSA-3700989Inferred only
TMEM219 regulates negative regulation of inflammatory responseBiological processgene ontology Q86XT9|GO:0050728Inferred only
TMEM219 regulates positive regulation of ERK1 and ERK2 cascadeBiological processgene ontology Q86XT9|GO:0070374Inferred only
TMEM219 regulates regulation of transforming growth factor beta1 productionBiological processgene ontology Q86XT9|GO:0032908Inferred only

Other names

2 names

Resolves to: TMEM219

Also called: IGFBP-3RTransmembrane protein 219

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