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Proteins/UNIPROT:Q8NEV4
Actin-dependent motor protein with a protein kinase activity, playing an essential role in hearing. Probably also plays a role in vision. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments..
Function from UniProtKB (Q8NEV4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
17 statements
17 statements · 3 reference databases · Subject: MYO3A · Sources: gene ontology, Hetionet, Reactome
3 reactions
1 name
Resolves to: MYO3A
Rhea RHEA:13065CC BY 4.0Reference data