Compound
hypotaurine
Zwitterionic form of hypotaurine arising from migration of a proton from the sulfonate group to the amino group; major species at pH 7.3.
Definition from ChEBI (CHEBI:57853), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound
- Formula
- C2H7NO2S
- Mass
- 109.15 g/mol
- Charge
- 0
- InChIKey
- VVIUBCNYACGLLV-UHFFFAOYSA-N
- SMILES
- [NH3+]CCS(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- SLC6A1ProteinUNIPROT:P30531transported byInferred only46 paths45 endpoints
- SLC6A6ProteinUNIPROT:P31641transported byInferred only34 paths34 endpoints
- FMO1ProteinUNIPROT:Q01740metabolized byInferred only20 paths10 endpoints
- taurineCompoundCHEBI:507393converted toInferred only16 paths6 endpoints
- FMO3ProteinUNIPROT:P31513metabolized byInferred only15 paths15 endpoints
- CSADProteinUNIPROT:Q9Y600substrate ofInferred only8 paths8 endpoints
- GADL1ProteinUNIPROT:Q6ZQY3substrate ofInferred only5 paths5 endpoints
- SLC6A13ProteinUNIPROT:Q9NSD5transported byInferred only4 paths4 endpoints
- SLC6A11ProteinUNIPROT:P48066transported byInferred only2 paths2 endpoints
What the reference databases state
Statements
14 statements
14 statements · 1 reference database · Subject: hypotaurine · Sources: Rhea
- 3-sulfino-L-alanine is converted to hypotaurineCompoundRhea RHEA:16877Inferred only
- hypotaurine is converted to 3-sulfino-L-alanineCompoundRhea RHEA:16877Inferred only
- cysteamine is converted to hypotaurineCompoundRhea RHEA:14409Inferred only
- hypotaurine is converted to taurineCompoundRhea RHEA:74111Inferred only
- hypotaurine is converted to taurineCompoundRhea RHEA:69819Inferred only
- hypotaurine is metabolised by FMO1ProteinRhea RHEA:69819Inferred only
- hypotaurine is metabolised by FMO1ProteinRhea RHEA:74111Inferred only
- hypotaurine is metabolised by FMO3ProteinRhea RHEA:69819Inferred only
- hypotaurine is a substrate of CSADProteinRhea RHEA:16877Inferred only
- hypotaurine is a substrate of GADL1ProteinRhea RHEA:16877Inferred only
- hypotaurine is transported by SLC6A1ProteinRhea RHEA:71243Inferred only
- hypotaurine is transported by SLC6A11ProteinRhea RHEA:71243Inferred only
Show the remaining 2
- hypotaurine is transported by SLC6A13ProteinRhea RHEA:71243Inferred only
- hypotaurine is transported by SLC6A6ProteinRhea RHEA:71243Inferred only
Reactions
6 reactions
cysteamine+dioxygenhypotaurine+hydron
Catalysed by ADO
Reaction pageLeft to rightBalanced
Rhea RHEA:14409CC BY 4.0Reference data
3-sulfino-L-alanine+hydronhypotaurine+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:16877CC BY 4.0Reference data
hypotaurine+pyruvateCHEBI:142501+L-alanine
Reaction pageDirection not assertedBalanced
Rhea RHEA:58056CC BY 4.0Reference data
hypotaurine+NADPH(4-)+dioxygen+hydrontaurine+NADP(3-)+water
Reaction pageLeft to rightBalanced
Rhea RHEA:69819CC BY 4.0Reference data
hypotaurine+chloride+2sodium(1+)hypotaurine+chloride+2sodium(1+)
Transported by SLC6A1 or SLC6A6 or SLC6A11 or SLC6A13
Reaction pageLeft to rightBalanced
Rhea RHEA:71243CC BY 4.0Reference data
hypotaurine+NADH(2-)+dioxygen+hydrontaurine+NAD(1-)+water
Catalysed by FMO1
Reaction pageLeft to rightBalanced
Rhea RHEA:74111CC BY 4.0Reference data
Where it reaches
9 systems, 23 regions, 80 tissues, 83 transporter routes — routes, not measurements: transporters known to carry hypotaurine are expressed there, and no source reports it arriving.
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Other names
4 names
Resolves to: hypotaurine
- Also called
- 2-ammonioethanesulfinate2-azaniumylethane-1-sulfinate2-mmonioethane-1-sulfinate
- Systematic name
- 2-azaniumylethanesulfinate