Proteins/UNIPROT:Q5T5C0

STXBP5

ProteinUNIPROT:Q5T5C0

Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity)..

Function from UniProtKB (Q5T5C0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 3 reference databases · Subject: STXBP5 · Sources: gene ontology, Hetionet, WikiPathways

Order

ADGRL1 covaries with STXBP5ProteinHetionet hetionet:covaries:134957-22859Inferred only
STXBP5 covaries with ADOProteinHetionet hetionet:covaries:134957-84890Inferred only
STXBP5 covaries with ATF5ProteinHetionet hetionet:covaries:134957-22809Inferred only
STXBP5 covaries with CDX2ProteinHetionet hetionet:covaries:1045-134957Inferred only
STXBP5 covaries with CETPProteinHetionet hetionet:covaries:1071-134957Inferred only
STXBP5 covaries with CYP27C1ProteinHetionet hetionet:covaries:134957-339761Inferred only
STXBP5 covaries with EFR3BProteinHetionet hetionet:covaries:134957-22979Inferred only
STXBP5 covaries with POLR2DProteinHetionet hetionet:covaries:134957-5433Inferred only
STXBP5 covaries with RAC3ProteinHetionet hetionet:covaries:134957-5881Inferred only
STXBP5 covaries with RFNGProteinHetionet hetionet:covaries:134957-5986Inferred only
SNAP23 interacts with STXBP5ProteinHetionet hetionet:interacts:134957-8773Inferred only
STX1A interacts with STXBP5ProteinHetionet hetionet:interacts:134957-6804Inferred only

Show the remaining 4

STX4 interacts with STXBP5ProteinHetionet hetionet:interacts:134957-6810Inferred only
STXBP5 participates in SNARE complex machinery in exocytosisPathwayWikiPathways WP5621Inferred only
STXBP5 regulates positive regulation of exocytosisBiological processgene ontology Q5T5C0|GO:0045921Inferred only
STXBP5 regulates regulation of exocytosisBiological processgene ontology Q5T5C0|GO:0017157Inferred only

Other names

3 names

Resolves to: STXBP5

Also called: Lethal(2) giant larvae protein homolog 3LLGL3Tomosyn-1

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