(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

40 compounds within 3 steps: 2 in 1, 3 in 2, 35 in 3

One step

quinolinic acidReach from here →
1. 2-amino-3-carboxymuconate semialdehyde to quinolinate conversion
No catalyst recordedcytosol
3-hydroxyanthranilateReach from here →
1. 3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde
Catalysed by HAAO

Two steps

nicotinic acid D-ribonucleotideReach from here →
1. 2-amino-3-carboxymuconate semialdehyde to quinolinate conversion
2. Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)
Catalysed by QPRTcytosol
sulfateReach from here →
1. 2-amino-3-carboxymuconate semialdehyde to quinolinate conversion
2. Transport of Quinolinic Acid
Catalysed by SLC22A6cytosol, extracellular spaceOne of 2 routes
3-hydroxy-L-kynurenineReach from here →

Three steps

pregnenolone sulfateReach from here →
Catalysed by SLC22A6, STScytosol, extracellular space, Golgi apparatusOne of 2 routes
androsterone 3alpha-sulfateReach from here →
Catalysed by SLC22A6

3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde

3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)

Catalysed by HAAO, KYNU

, STS

cytosol, extracellular space

One of 3 routes

cholesterol sulfateReach from here →

Catalysed by SLC22A6, STScytosol, extracellular space, Golgi apparatusOne of 2 routes

5alpha-dihydrotestosterone sulfateReach from here →

Catalysed by SLC22A6, STScytosol, extracellular spaceOne of 3 routes

an aryl sulfateReach from here →

Catalysed by SLC22A6, ARSL, ARSF, ARSK and 3 morecytosol, extracellular space

(S)-malateReach from here →

Catalysed by SLC22A6, SLC25A10cytosol, extracellular space, mitochondrial matrixOne of 4 routes

malonateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30, SLC25A10cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

oxalic acidReach from here →

Catalysed by SLC22A6, SLC26A6cytosol, extracellular space

sulfiteReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

3,3'-diiodo-L-thyronine sulfateReach from here →

Catalysed by SLC22A6, STScytosol, extracellular space, Golgi apparatusOne of 2 routes

fumaric acidReach from here →

Catalysed by SLC22A6, SLC25A10cytosol, extracellular space, mitochondrial matrixOne of 2 routes

folic acidReach from here →

Catalysed by SLC22A6, SLC22A8, SLC22A7cytosol, extracellular spaceOne of 2 routes

a dicarboxylateReach from here →

Catalysed by SLC22A6, SLC25A35, SLC25A34cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

chlorine(.)Reach from here →

Catalysed by SLC22A6, SLC26A6cytosol, extracellular space

D-aspartateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

L-aspartateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

oxalateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC26A2, SLC25A30 and 2 morecytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

maleateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

malonic acidReach from here →

Catalysed by SLC22A6, SLC25A10cytosol, extracellular space, mitochondrial matrixOne of 2 routes

(2R,3R)-tartrateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

(S,S)-tartrateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

(3R)-citramalateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

(3S)-citramalateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30cytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

thiosulfateReach from here →

Catalysed by SLC22A6, SLC25A14, SLC25A30, SLC26A1 and 1 morecytosol, extracellular space, inner side of the membrane, outer side of the membraneOne of 2 routes

glycineReach from here →

Catalysed by HAAO, KYNU, KYAT3, AADAT

N-sulfo-D-glucosamineReach from here →

Catalysed by SLC22A6, SGSHcytosol, extracellular space

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by SLC22A6, STScytosol, extracellular space

L-kynurenineReach from here →

Catalysed by HAAO, KYNU, KMO

L-alanineReach from here →

Catalysed by HAAO, KYNU

adenosine 5'-phosphosulfateReach from here →

Catalysed by SLC22A6, PAPSS1, PAPSS2cytosol, extracellular spaceOne of 4 routes

deamido-NAD(+)Reach from here →

Catalysed by QPRT, NMNAT3cytosol, mitochondrial matrixOne of 3 routes

beta-D-ribosylnicotinateReach from here →

Catalysed by QPRT, ACP3, NT5E, NT5C and 5 morecytosol

estrone 3-sulfateReach from here →

Catalysed by SLC22A6, STScytosol, extracellular space

(5-hydroxyindol-3-yl)acetateReach from here →

Catalysed by SLC22A6, SLC4A1cytosol, extracellular spaceOne of 2 routes

xanthurenateReach from here →

Catalysed by HAAO, KYNU, KYAT3, AADAT