Compound

(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde

A dicarboxylic acid anion that is the major structure at pH 7.3 of cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid

Definition from ChEBI (CHEBI:77612), read 2026-09-23. CC BY 4.0.

CHEBI:77612ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C7H6NO5
Mass: 184.127 g/mol
Charge: -1
InChIKey: KACPVQQHDVBVFC-OIFXTYEKSA-M
SMILES: [NH3+]/C(C(=O)[O-])=C(/C=CC=O)C(=O)[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde · Sources: Human-GEM, Rhea

Order

(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is converted to 3-hydroxyanthranilateCompoundRhea RHEA:17953Inferred only
3-hydroxyanthranilate is converted to (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydeCompoundRhea RHEA:17953Inferred only
3-hydroxyanthranilic acid is converted to (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydeCompoundHuman-GEM MAR04228Inferred only
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is converted to quinolinateCompoundRhea RHEA:25147Inferred only
quinolinate is converted to (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydeCompoundRhea RHEA:25147Inferred only
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is converted to quinolinic acidCompoundHuman-GEM MAR04250Inferred only
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is a substrate of ACMSDProteinHuman-GEM MAR04231Inferred only
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is a substrate of ACMSDProteinRhea RHEA:16557Inferred only
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde is a substrate of HAAOProteinRhea RHEA:17953Inferred only

Reactions

6 reactions

3-hydroxyanthranilic acid+dioxygen(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde+proton
Catalysed by HAAO
Reaction pageLeft to rightBalancedEC 1.13.11.6cytosol
Human-GEM MAR04228CC BY 4.0Reference data
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde+protonMAM00633c+carbon dioxide
Catalysed by ACMSD
Reaction pageLeft to rightBalancedEC 4.1.1.45cytosol
Human-GEM MAR04231CC BY 4.0Reference data
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydeproton+water+quinolinic acid
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR04250CC BY 4.0Reference data
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde+hydronCHEBI:77634+carbon dioxide
Catalysed by ACMSD
Reaction pageLeft to rightBalanced
Rhea RHEA:16557CC BY 4.0Reference data
3-hydroxyanthranilate+dioxygen(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde
Catalysed by HAAO
Reaction pageDirection not assertedBalanced
Rhea RHEA:17953CC BY 4.0Reference data
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydequinolinate+water+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:25147CC BY 4.0Reference data

Other names

2 names

Resolves to: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde

Also called: (2Z)-2-ammonio-3-[(1Z)-3-oxoprop-1-en-1-yl]but-2-enedioate
Systematic name: (2Z)-2-azaniumyl-3-[(1Z)-3-oxoprop-1-en-1-yl]but-2-enedioate