CHEBI:17797

Three steps

• uracilReach from here →
  1. D-Ribose 1,5-phosphomutase
  2. uridine:phosphate alpha-D-ribosyltransferase
  3. uridine:phosphate alpha-D-ribosyltransferase

  Catalysed by PGM2, UPP2, UPP1cytosolOne of 2 routes

• xanthineReach from here →
  1. D-Ribose 1,5-phosphomutase
  2. xanthosine:orthophosphate ribosyltransferase
  3. xanthosine:orthophosphate ribosyltransferase

  Catalysed by PGM2, PNPcytosol

• CHEBI:17808Reach from here →
  1. D-Ribose 1,5-phosphomutase
  2. uridine:phosphate alpha-D-ribosyltransferase
  3. uridine/cytidine kinase (ITP)

  Catalysed by PGM2, UPP2, UPP1, UCK2 and 1 morecytosol

• keto-D-fructose 1-phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase

  Catalysed by TKT, TKTL1, TKTL2, TPI1 and 3 morecytosol

• N(1)-(5-phospho-D-ribosyl)glycinamideReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. phosphoribosyl pyrophosphate amidotransferase (glutamine)
  3. 5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)

  Catalysed by PRPS2, PRPS1L1, PRPS1, PPAT and 1 morecytosol

• CHEBI:18381Reach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. IMP:diphosphate phospho-D-ribosyltransferase
  3. IMP 1,2-hydrolase (decyclizing)

  Catalysed by PRPS2, PRPS1L1, PRPS1, HPRT1 and 1 morecytosol

• hydroxyacetoneReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
  3. aldose reductase (methylglyoxal)

  Catalysed by TKT, TKTL1, TKTL2, AKR7A2 and 2 morecytosolOne of 2 routes

• CHEBI:28862Reach from here →
  1. D-Ribose 1,5-phosphomutase
  2. adenosine:phosphate alpha-D-ribosyltransferase
  3. Adenosine Kinase

  Catalysed by PGM2, PNPcytosol

• 2'-deoxyinosineReach from here →
  1. D-Ribose 1,5-phosphomutase
  2. inosine:phosphate alpha-D-ribosyltransferase
  3. dIMP + inosine = 2'-deoxyinosine + IMP

  Catalysed by PGM2, PNP, NT5C2cytosol

• quinolinateReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)
  3. nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)

  Catalysed by PRPS2, PRPS1L1, PRPS1, QPRTcytosol

• nicotinateReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)
  3. 5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate

  Catalysed by PRPS2, PRPS1L1, PRPS1, QPRT and 1 morecytosol

• beta-D-fructose 1,6-bisphosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate
  3. beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate

  Catalysed by TKT, TKTL1, TKTL2, TALDO1 and 2 morecytosolOne of 2 routes

• D-glucopyranose 6-phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase
  3. D-glucose-6-phosphate aldose-ketose-isomerase

  Catalysed by TKT, TKTL1, TKTL2, TALDO1 and 1 morecytosol

• 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamideReach from here →
  1. D-Ribose 1,5-phosphomutase
  2. purine nucleoside phosphorylase (nicotinamide)
  3. 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol

  Catalysed by PGM2, PNP, NQO2cytosol

• (R)-S-lactoylglutathioneReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
  3. (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)

  Catalysed by TKT, TKTL1, TKTL2, GLO1 and 1 morecytosolOne of 2 routes

• N(6)-(1,2-dicarboxyethyl)-AMPReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. IMP:diphosphate phospho-D-ribosyltransferase
  3. IMP:L-aspartate ligase (GDP-forming)

  Catalysed by PRPS2, PRPS1L1, PRPS1, HPRT1 and 2 morecytosolOne of 2 routes

• dihydroxyacetone phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
  3. dihydroxyacetone phosphate = methylglyoxal + phosphate

  Catalysed by TKT, TKTL1, TKTL2, TPI1cytosol

• dGMPReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
  3. dGMP + inosine = 2'-deoxyguanosine + IMP

  Catalysed by PRPS2, PRPS1L1, PRPS1, HPRT1 and 1 morecytosol

• alpha-D-ribose 1-phosphateReach from here →
  1. D-Ribose 1,5-phosphomutase
  2. inosine:phosphate alpha-D-ribosyltransferase
  3. inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine

  Catalysed by PGM2, PNP, LACC1cytosolOne of 4 routes

• alpha-D-glucose 6-phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate
  3. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate

  Catalysed by TKT, TKTL1, TKTL2, TALDO1 and 1 morecytosol

• (2R)-3-phosphoglycerateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)
  3. ATP:3-phospho-D-glycerate 1-phosphotransferase

  Catalysed by TKT, TKTL1, TKTL2, GAPDHS and 4 morecytosolOne of 9 routes

• 1-hexadecanoylglycerone 3-phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. glyceronephosphate O-acyltransferase (DHAP)

  Catalysed by TKT, TKTL1, TKTL2, TPI1 and 1 morecytosol, peroxisome

• alpha-D-glucose 1,6-bisphosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)
  3. 3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase

  Catalysed by TKT, TKTL1, TKTL2, GAPDHS and 2 morecytosolOne of 3 routes

• deamido-NAD(+)Reach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)
  3. Nicotinate-Nucleotide Adenylyltransferase, Mitochondrial

  Catalysed by PRPS2, PRPS1L1, PRPS1, QPRT and 1 morecytosol, mitochondrial matrixOne of 4 routes

• beta-D-ribosylnicotinateReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)
  3. nicotinate D-ribonucleotide phosphohydrolase

  Catalysed by PRPS2, PRPS1L1, PRPS1, QPRT and 8 morecytosolOne of 2 routes

• D-glyceraldehyde 3-phosphateReach from here →
  1. D-ribose-5-phosphate aldose-ketose-isomerase
  2. D-ribulose 5-phosphate = D-xylulose 5-phosphate
  3. D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate

  Catalysed by RPIA, RPEL1, RPE, TKT and 2 moreendoplasmic reticulumOne of 6 routes

• dIMPReach from here →
  1. ATP:D-ribose-5-phosphate diphosphotransferase
  2. IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
  3. dIMP + inosine = 2'-deoxyinosine + IMP

  Catalysed by PRPS2, PRPS1L1, PRPS1, HPRT1 and 1 morecytosol

• D-ribulose 1-phosphateReach from here →
  1. transketolase (D-xylulose-5-phosphate)
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)

  Catalysed by TKT, TKTL1, TKTL2, TPI1 and 3 morecytosol