Compound

alpha-D-glucose 1,6-bisphosphate

A quadruply-charged organophosphate oxoanion arising from deprotonation of the phosphate OH groups of α-D-glucose 1,6-bisphosphate; major species at pH 7.3.

Definition from ChEBI (CHEBI:58392), read 2026-09-23. CC BY 4.0.

CHEBI:58392ChEBI

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Structure

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A generated conformer of alpha-D-glucose 1,6-bisphosphate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H10O12P2
Mass: 336.082 g/mol
Charge: -4
InChIKey: RWHOZGRAXYWRNX-VFUOTHLCSA-J
SMILES: O=P([O-])([O-])OC[C@H]1O[C@H](OP(=O)([O-])[O-])[C@H](O)[C@@H](O)[C@@H]1O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

6 statements

6 statements · 1 reference database · Subject: alpha-D-glucose 1,6-bisphosphate · Sources: Rhea

Order

alpha-D-glucose 1,6-bisphosphate is converted to alpha-D-glucose 1-phosphateCompoundRhea RHEA:13377Inferred only
alpha-D-glucose 1-phosphate is converted to alpha-D-glucose 1,6-bisphosphateCompoundRhea RHEA:13377Inferred only
alpha-D-glucose 1,6-bisphosphate is a substrate of PGM1ProteinRhea RHEA:68748Inferred only
alpha-D-glucose 1,6-bisphosphate is a substrate of PGM1ProteinRhea RHEA:68752Inferred only
alpha-D-glucose 1,6-bisphosphate is a substrate of PGM2ProteinRhea RHEA:68748Inferred only
alpha-D-glucose 1,6-bisphosphate is a substrate of PGM2ProteinRhea RHEA:68752Inferred only

Reactions

8 reactions

(2R)-3-phospho-glyceroyl phosphate+MAM01967c(2R)-3-phosphoglycerate+alpha-D-glucose 1,6-bisphosphate
Catalysed by PGM2L1
Reaction pageLeft to rightBalancedEC 2.7.1.106cytosol
Human-GEM MAR08585CC BY 4.0Reference data
alpha-D-glucose 1,6-bisphosphatealpha-D-glucose 1,6-bisphosphate
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR09187CC BY 4.0Reference data
alpha-D-glucose 1,6-bisphosphate
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09461CC BY 4.0Reference data
alpha-D-glucose 1-phosphate+ATP(4-)alpha-D-glucose 1,6-bisphosphate+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13377CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphate+alpha-D-glucose 1-phosphatealpha-D-glucose 1,6-bisphosphate+(2R)-3-phosphoglycerate+hydron
Catalysed by PGM2L1
Reaction pageLeft to rightBalanced
Rhea RHEA:16769CC BY 4.0Reference data
O-phospho-L-seryl-[protein]+alpha-D-glucose 1-phosphatealpha-D-glucose 1,6-bisphosphate+L-seryl-[protein]
Catalysed by PGM1 or PGM2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:68748CC BY 4.0Reference data
alpha-D-glucose 1,6-bisphosphate+L-seryl-[protein]O-phospho-L-seryl-[protein]+alpha-D-glucose 6-phosphate
Catalysed by PGM1 or PGM2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:68752CC BY 4.0Reference data
alpha-D-glucose 6-phosphate+(2R)-3-phospho-glyceroyl phosphatealpha-D-glucose 1,6-bisphosphate+(2R)-3-phosphoglycerate+hydron
Catalysed by PGM2L1
Reaction pageLeft to rightBalanced
Rhea RHEA:70911CC BY 4.0Reference data

Other names

7 names

Resolves to: alpha-D-glucose 1,6-bisphosphate

Also called: alpha-D-glucose 1,6-bisphosphate tetraanionα-D-glucose 1,6-bisphosphateα-D-glucose 1,6-bisphosphate tetraanion
Systematic name: 1,6-di-O-phosphonato-alpha-D-glucopyranose1,6-di-O-phosphonato-α-D-glucopyranosealpha-D-glucopyranose 1,6-bis(phosphate)α-D-glucopyranose 1,6-bis(phosphate)