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Proteins/UNIPROT:O75387
Uniport that mediates the transport of neutral amino acids such as L-leucine, L-isoleucine, L-valine, and L-phenylalanine. The transport activity is sodium ions-independent, electroneutral and mediated by a facilitated diffusion. Mediates the efflux of 3,3'-diiodo-L-thyronine (3,3'-T2) and 3-iodo-L-tyrosine (MIT)..
Function from UniProtKB (O75387), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 6 · transported by
6 compounds
6 compounds.
0 reported routes6 assembled routes
70 statements
70 statements · 8 reference databases · Subject: SLC43A1 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
24 reactions
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC43A2
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR05073CC BY 4.0Reference data
6 names
Resolves to: SLC43A1
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05074CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC7A10 or SLC43A1 or SLC6A18
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05076CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05078CC BY 4.0Reference data
L-seryl residueL-seryl residue
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC7A10 or SLC43A1 or SLC7A7
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05079CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC16A10 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05080CC BY 4.0Reference data
L-phenylalanineL-phenylalanine
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC16A10 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05082CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC7A10 or SLC43A1 or SLC7A7 or SLC7A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05084CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05085CC BY 4.0Reference data
Transported by SLC7A8 or SLC36A1 or SLC43A1 or SLC7A7
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR05087CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05088CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05089CC BY 4.0Reference data