beta-D-glucosyl-(1->3)-O-chenodeoxycholate

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose

Catalysed by GBA2

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose

Catalysed by GBA2

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose
2. Chenodeoxycholic acid 6alpha-hydroxylase

Catalysed by GBA2, CYP3A4cytosol

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose
2. solute carrier organic anion transporter (chenodiol)

Catalysed by GBA2, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose
2. chenodeoxycholate:CoA ligase (AMP-forming)
3. bile acid-CoA: amino acid N-acyltransferase

Catalysed by GBA2, SLC27A5, BAATcytosol, peroxisomeOne of 8 routes

1. beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O = chenodeoxycholate + D-glucose
2. solute carrier organic anion transporter (chenodiol)
3. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)