Compound
alpha,alpha-trehalose
A trehalose in which both glucose residues have α-configuration at the anomeric carbon.
Definition from ChEBI (CHEBI:16551), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound
- Formula
- C12H22O11
- Mass
- 342.297 g/mol
- Charge
- 0
- InChIKey
- HDTRYLNUVZCQOY-LIZSDCNHSA-N
- SMILES
- OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
9 statements
9 statements · 2 reference databases · Subject: alpha,alpha-trehalose · Sources: Human-GEM, Rhea
- alpha,alpha-trehalose is converted to D-glucoseCompoundHuman-GEM MAR04837Inferred only
- alpha,alpha-trehalose is converted to D-glucoseCompoundHuman-GEM MAR01812Inferred only
- alpha,alpha-trehalose is converted to maltoseCompoundRhea RHEA:15145Inferred only
- maltose is converted to alpha,alpha-trehaloseCompoundRhea RHEA:15145Inferred only
- alpha,alpha-trehalose is a substrate of PGGHGProteinHuman-GEM MAR01812Inferred only
- alpha,alpha-trehalose is a substrate of TREHProteinRhea RHEA:32675Inferred only
- alpha,alpha-trehalose is a substrate of TREHProteinHuman-GEM MAR04837Inferred only
- alpha,alpha-trehalose is a substrate of TREHProteinHuman-GEM MAR01812Inferred only
- alpha,alpha-trehalose is transported by SLC2A8ProteinRhea RHEA:17629Inferred only
Reactions
18 reactions
water+alpha,alpha-trehalose2D-glucose
Reaction pageLeft to rightBalancedEC 3.2.1.28cytosol
Human-GEM MAR01812CC BY 4.0Reference data
water+alpha,alpha-trehalose2D-glucose
Catalysed by TREH
Reaction pageLeft to rightBalancedEC 3.2.1.28extracellular space
Human-GEM MAR04837CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09426CC BY 4.0Reference data
alpha,alpha-trehalosealpha,alpha-trehalose
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR10481CC BY 4.0Reference data
Reaction pageDirection not assertedBalanced
Rhea RHEA:15145CC BY 4.0Reference data
alpha,alpha-trehalose+hydrogenphosphatealpha-D-glucose+alpha-D-glucose 1-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:16257CC BY 4.0Reference data
alpha,alpha-trehalosealpha,alpha-trehalose
Transported by SLC2A8
Reaction pageRight to leftBalanced
Rhea RHEA:17629CC BY 4.0Reference data
CHEBI:58429+wateralpha,alpha-trehalose+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:23420CC BY 4.0Reference data
2CHEBI:18234CHEBI:18195+alpha,alpha-trehalose
Reaction pageDirection not assertedBalanced
Rhea RHEA:23472CC BY 4.0Reference data
alpha,alpha-trehalose+hydrogenphosphateCHEBI:57684+D-glucose
Reaction pageDirection not assertedBalanced
Rhea RHEA:23512CC BY 4.0Reference data
ADP-alpha-D-glucose+D-glucosealpha,alpha-trehalose+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:25408CC BY 4.0Reference data
alpha,alpha-trehalose+wateralpha-D-glucose+beta-D-glucose
Catalysed by TREH
Reaction pageDirection not assertedBalanced
Rhea RHEA:32675CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 2 tissues, 2 transporter routes — routes, not measurements: transporters known to carry alpha,alpha-trehalose are expressed there, and no source reports it arriving.
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Other names
16 names
Resolves to: alpha,alpha-trehalose
- Also called
- (Glc)2alpha-D-Glcp-(11)-alpha-D-Glcpalpha-D-glucopyranosyl-alpha-D-glucopyranosidealpha-D-Trehalosealpha-trehalosealpha,alpha'-TrehaloseD-(+)-trehaloseergot sugarmycoseTrehaloseα-D-Glcp-(1↔1)-α-D-Glcpα-D-glucopyranosyl-α-D-glucopyranosideα-D-Trehaloseα-trehalose
- Systematic name
- alpha-D-glucopyranosyl alpha-D-glucopyranosideα-D-glucopyranosyl α-D-glucopyranoside