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alpha-D-glucose

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

16 compounds within 3 steps: 3 in 1, 2 in 2, 11 in 3

Does it reach a compound?

One step

beta-D-glucoseReach from here →
1. alpha-D-glucose[n] = beta-D-glucose[n]
Catalysed by GALMnucleusOne of 3 routes
alpha,alpha-trehaloseReach from here →
1. alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose
Catalysed by TREH
sucroseReach from here →
1. sucrose + H2O = beta-D-fructose + alpha-D-glucose
Catalysed by SI

Two steps

beta-D-fructoseReach from here →
1. sucrose + H2O = beta-D-fructose + alpha-D-glucose
2. sucrose glucohydrolase
Catalysed by SI, MGAM, GANCextracellular spaceOne of 2 routes
D-glucoseReach from here →
1. alpha-D-glucose[n] = beta-D-glucose[n]
2. D-glucose 1-epimerase
Catalysed by GALMnucleus, cytosolOne of 4 routes

Three steps

beta-D-fructose 1-phosphateReach from here →
Catalysed by SI, MGAM, GANC, KHKextracellular space
keto-D-fructose 6-phosphateReach from here →
Catalysed by and 3 more

extracellular space, cytosol

One of 3 routes

CHEBI:16174Reach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
dATP:D-glucose 6-phosphotransferase

Catalysed by GALM, HK1, HK2, HK3 and 1 morenucleus, cytosolOne of 2 routes

D-glucono-1,5-lactoneReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)

Catalysed by GALM, H6PDnucleus, cytosolOne of 2 routes

lactoseReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)

Catalysed by GALM, B4GALT2, B4GALT1nucleus, cytosol

CHEBI:17808Reach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
ITP:D-glucose 6-phosphotransferase

Catalysed by GALM, HK1, HK2, HK3 and 1 morenucleus, cytosolOne of 2 routes

D-glucitolReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
Aldehyde Reductase

Catalysed by GALMnucleus, cytosolOne of 4 routes

keto-D-fructose 1-phosphateReach from here →

sucrose + H2O = beta-D-fructose + alpha-D-glucose
sucrose glucohydrolase
ATP:D-fructose 1-phosphotransferase

Catalysed by SI, MGAM, GANC, KHKextracellular space, cytosol

alpha-lactoseReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
UDP-alpha-D-galactose:D-glucose 4-beta-D-galactosyltransferase

Catalysed by GALM, B4GALT2, LALBA, B4GALT1nucleus, cytosol, Golgi apparatus

D-glucopyranose 6-phosphateReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
ATP:D-glucose 6-phosphotransferase

Catalysed by GALM, HK1, GCK, HK2 and 2 morenucleus, cytosolOne of 5 routes

D-glucose 6-phosphateReach from here →

alpha-D-glucose[n] = beta-D-glucose[n]
D-glucose 1-epimerase
D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)

Catalysed by GALM, ADPGKnucleus, cytosolOne of 2 routes