Fe(II)-heme o

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

184 compounds within 3 steps: 4 in 1, 73 in 2, 107 in 3

One step

AH2Reach from here →
1. Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2
Catalysed by COX15
(2E,6E)-farnesyl diphosphateReach from here →
1. heme b + (2E,6E)-farnesyl diphosphate + H2O = Fe(II)-heme o + diphosphate
Catalysed by COX10
heme bReach from here →
1. heme b + (2E,6E)-farnesyl diphosphate + H2O = Fe(II)-heme o + diphosphate
Catalysed by COX10
Fe(II)-heme aReach from here →
1. Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2
Catalysed by COX15

Two steps

Reach from here →

Catalysed by COX15, AIFM1, PYROXD1One of 70 routes

(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by COX15, PTGS2

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by COX15, PTGS2

prostaglandin H3Reach from here →

Catalysed by COX15, PTGS2

13-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by COX15, PTGS2

9-hydroxy-(10E,12Z)-octadecadienoateReach from here →

Catalysed by COX15, PTGS2

(13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by COX15, PTGS1, PTGS2

2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by COX15, PTGS2

2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by COX15, PTGS2

2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by COX15, PTGS2

2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by COX15, PTGS2

2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →

Catalysed by COX15, PTGS2

squaleneReach from here →

Catalysed by COX10, FDFT1endoplasmic reticulumOne of 3 routes

cob(II)alaminReach from here →

Catalysed by COX15, MTRR

iodideReach from here →

Catalysed by COX15, DIO1, DIO3One of 22 routes

nitric oxideReach from here →

Catalysed by COX15, SUOX

3'-deoxy-3',4'-didehydro-CTPReach from here →

Catalysed by COX15, RSAD2

(S)-2-hydroxyglutarateReach from here →

Catalysed by COX15, L2HGDH

COReach from here →

Catalysed by COX10, HMOX1, HMOX2cytosolOne of 2 routes

5'-deoxyadenosineReach from here →

Catalysed by COX15, CDK5RAP1One of 4 routes

3,3',5'-triiodo-L-thyronine sulfateReach from here →

Catalysed by COX15, DIO1

3,3'-diiodo-L-thyronineReach from here →

Catalysed by COX15, DIO1, DIO3One of 2 routes

3,3'-diiodo-L-thyronine sulfateReach from here →

Catalysed by COX15, DIO1One of 2 routes

3',5'-diiodo-L-thyronineReach from here →

Catalysed by COX15, DIO3

3-iodothyronamineReach from here →

Catalysed by COX15, DIO1, DIO3One of 2 routes

3-iodo-L-thyronineReach from here →

Catalysed by COX15, DIO1, DIO3One of 2 routes

3'-iodo-L-thyronineReach from here →

Catalysed by COX15, DIO1, DIO2One of 2 routes

L-thyronineReach from here →

Catalysed by COX15, DIO3

thyronamineReach from here →

Catalysed by COX15, DIO3

3'-iodothyronamineReach from here →

Catalysed by COX15, DIO1, DIO2One of 2 routes

3,3'-diiodothyronamineReach from here →

Catalysed by COX15, DIO1, DIO2One of 2 routes

3',5'-diiodothyronamineReach from here →

Catalysed by COX15, DIO3

3,3',5'-triiodothyronamineReach from here →

Catalysed by COX15, DIO3

iron(2+)Reach from here →

Catalysed by COX10, HMOX1, HMOX2cytosolOne of 2 routes

hydrogenselenideReach from here →

Catalysed by COX15, SCLY

25-hydroxycholesterolReach from here →

Catalysed by COX15, CH25H

all-trans-13,14-dihydroretinolReach from here →

Catalysed by COX15, RETSAT

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by COX15, DIO1, DIO2

deoxyhemoglobinReach from here →

Catalysed by COX10cytosol

3,3',5'-triiodo-L-thyronineReach from here →

Catalysed by COX15, DIO1, DIO3

presqualene diphosphateReach from here →

Catalysed by COX10, FDFT1cytosolOne of 3 routes

prostaglandin H2Reach from here →

Catalysed by COX15, PTGS1, PTGS2One of 2 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by COX15, TBXAS1, PTGS2, PTGIS

L-methionineReach from here →

Catalysed by COX15, CDK5RAP1One of 4 routes