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Proteins/UNIPROT:O95749
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins..
Function from UniProtKB (O95749), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
77 statements
77 statements · 8 reference databases · Subject: GGPS1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
7 reactions
MAM01706c+isopentenyl diphosphate(2E)-geranyl diphosphate+diphosphate(3-)
Reaction pageLeft to rightBalancedEC 2.5.1.1, 2.5.1.10, 2.5.1.29cytosol
Human-GEM MAR01457CC BY 4.0Reference data
(2E)-geranyl diphosphate+isopentenyl diphosphate(2E,6E)-farnesyl diphosphate+diphosphate(3-)
8 names
Resolves to: GGPS1
Human-GEM MAR01460CC BY 4.0Reference data
MAM01706c+(2E,6E)-farnesyl diphosphatediphosphate(3-)+MAM03026c
Reaction pageLeft to rightBalancedEC 2.5.1.10cytosol
Human-GEM MAR01532CC BY 4.0Reference data
(2E,6E)-farnesyl diphosphate+isopentenyl diphosphatediphosphate(3-)+(2E,6E,10E)-geranylgeranyl diphosphate
Catalysed by GGPS1
Reaction pageLeft to rightBalancedEC 2.5.1.29cytosol
Human-GEM MAR11408CC BY 4.0Reference data
isopentenyl diphosphate+(2E,6E)-farnesyl diphosphate(2E,6E,10E)-geranylgeranyl diphosphate+diphosphate(3-)
Catalysed by GGPS1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17653CC BY 4.0Reference data
isopentenyl diphosphate+(2E)-geranyl diphosphate(2E,6E)-farnesyl diphosphate+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:19361CC BY 4.0Reference data
isopentenyl diphosphate+CHEBI:57623(2E)-geranyl diphosphate+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:22408CC BY 4.0Reference data