Structure
Loading the model…
- Class
- Organic compound
- Formula
- C30H50
- Mass
- 410.73 g/mol
- Charge
- 0
- InChIKey
- YYGNTYWPHWGJRM-AAJYLUCBSA-N
- SMILES
- CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C=C(C)CC/C=C(C)CCC=C(C)C
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
12 statements
12 statements · 2 reference databases · Subject: squalene · Sources: Human-GEM, Rhea
- (2E,6E)-farnesyl diphosphate is converted to squaleneCompoundRhea RHEA:32299Inferred only
- (2E,6E)-farnesyl diphosphate is converted to squaleneCompoundHuman-GEM MAR01715Inferred only
- (2E,6E)-farnesyl diphosphate is converted to squaleneCompoundRhea RHEA:32295Inferred only
- squalene is converted to (S)-2,3-epoxysqualeneCompoundHuman-GEM MAR01470Inferred only
- squalene is converted to (S)-2,3-epoxysqualeneCompoundHuman-GEM MAR01714Inferred only
- presqualene diphosphate is converted to squaleneCompoundHuman-GEM MAR02147Inferred only
- presqualene diphosphate is converted to squaleneCompoundRhea RHEA:22228Inferred only
- presqualene diphosphate is converted to squaleneCompoundRhea RHEA:22232Inferred only
- presqualene diphosphate is converted to squaleneCompoundHuman-GEM MAR01467Inferred only
- squalene is a substrate of SQLEProteinRhea RHEA:25282Inferred only
- squalene is a substrate of SQLEProteinHuman-GEM MAR01470Inferred only
- squalene is a substrate of SQLEProteinHuman-GEM MAR01714Inferred only
Reactions
21 reactions
proton+NADPH(4-)+presqualene diphosphateNADP(3-)+diphosphate(3-)+squalene
Catalysed by FDFT1
Reaction pageLeft to rightBalancedEC 2.5.1.21cytosol
Human-GEM MAR01467CC BY 4.0Reference data
proton+NADPH(4-)+dioxygen+squalenewater+NADP(3-)+(S)-2,3-epoxysqualene
Catalysed by SQLE
Reaction pageLeft to rightBalancedEC 1.14.14.17cytosol
Human-GEM MAR01470CC BY 4.0Reference data
proton+NADPH(4-)+dioxygen+squalenewater+NADP(3-)+(S)-2,3-epoxysqualene
Catalysed by SQLE
Reaction pageLeft to rightBalancedEC 1.14.14.17endoplasmic reticulum
Human-GEM MAR01714CC BY 4.0Reference data
2(2E,6E)-farnesyl diphosphate+proton+NADPH(4-)NADP(3-)+2diphosphate(3-)+squalene
Catalysed by FDFT1
Reaction pageLeft to rightBalancedEC 2.5.1.21endoplasmic reticulum
Human-GEM MAR01715CC BY 4.0Reference data
proton+NADPH(4-)+presqualene diphosphateNADP(3-)+diphosphate(3-)+squalene
Catalysed by FDFT1
Reaction pageLeft to rightBalancedEC 2.5.1.21endoplasmic reticulum
Human-GEM MAR02147CC BY 4.0Reference data
Reaction pageLeft to rightBalancedendoplasmic reticulum, cytosol
Human-GEM MAR11840CC BY 4.0Reference data
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR11841CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11842CC BY 4.0Reference data
Reaction pageDirection not assertedBalanced
Rhea RHEA:16561CC BY 4.0Reference data
squaleneCHEBI:4648
Reaction pageDirection not assertedBalanced
Rhea RHEA:17637CC BY 4.0Reference data
presqualene diphosphate+NADH(2-)+hydronsqualene+diphosphate(3-)+NAD(1-)
Catalysed by FDFT1
Reaction pageLeft to rightBalanced
Rhea RHEA:22228CC BY 4.0Reference data
presqualene diphosphate+NADPH(4-)+hydronsqualene+diphosphate(3-)+NADP(3-)
Catalysed by FDFT1
Reaction pageLeft to rightBalanced
Rhea RHEA:22232CC BY 4.0Reference data
On the label
Labelled products
32 products
Source: NIH DSLD · Ingredient: squalene · 32 products · Declared amount per serving: 1.5–1,000 mg (31 products)
31 labels state an amount1 does not
- Advanced ResearchSqualene 500 mgShark Liver Oil500 mgper 1 Softgel(s)DSLD:273594
- Advanced ResearchSqualene 500 mgShark Liver Oil500 mgper 1 Softgel(s)DSLD:275323
- Allergy Research GroupTocomin SupraBio Tocotrienols 100 mg6.5 mgper 1 Softgel(s)DSLD:258398
- Allergy Research GroupTocomin SupraBio Tocotrienols 100 mg6.5 mgper 1 Softgel(s)DSLD:258399
- Allergy Research GroupTocomin SupraBio Tocotrienols 200 mg13 mgper 1 Softgel(s)DSLD:258402
- Allergy Research GroupTocomin SupraBio Tocotrienols 200 mg13 mgper 1 Softgel(s)DSLD:304284
- Cardiovascular ResearchSqualeneShark Liver Oil1,000 mgper 1 Softgel(s)DSLD:283463
- CarlsonTocomin SupraBio3 mgper 1 Softgel(s)DSLD:309236
- CarlsonTocomin SupraBio3 mgper 1 Softgel(s)DSLD:309938
- CarotecVitamin E EVNol SupraBioamount not statedper 2 Softgel(s)DSLD:282147
- Endurance Products CompanyMixed Tocotrienols 50 mg6.6 mgper 1 Softgel(s)DSLD:177925
- Healthy OriginsTocomin SupraBio12.5 mgper 1 Softgel(s)DSLD:268904
Show the remaining 20
- Healthy OriginsTocomin SupraBio12.5 mgper 1 Softgel(s)DSLD:269123
- Kala HealthVitamin E Ultra Tocotrienols20 mgper 1 Softgel Capsule(s)DSLD:311350
- Kala HealthVitamin E Ultra Tocotrienols 200 mg Vegan20 mgper 1 Softgel Capsule(s)DSLD:311349
- Kala HealthVitamin E Ultra Tocotrienols 200 mg Vegan20 mgper 1 Softgel Capsule(s)DSLD:311351
- Kala HealthVitamin E Ultra Tocotrienols 200 mg Vegan No Tocopherols20 mgper 1 Softgel Capsule(s)DSLD:311352
- Kala HealthVitamin E Vegan 450 IU10 mgper 1 Softgel Capsule(s)DSLD:311353
- Kala HealthVitamin E-T85 mgper 1 Softgel Capsule(s)DSLD:311361
- Kala HealthVitamin E-T8 Vegan5 mgper 1 Softgel(s)DSLD:311362
- Kala HealthVitamin E-T8 Vegan 150 IU5 mgper 1 Capsule(s)DSLD:311363
- Kala HealthVitamin E-T8 Vegan 400 IU5 mgper 1 Softgel Capsule(s)DSLD:311364
- MegaFoodVitamin E Complete 86 mgper 1 Capsule(s)DSLD:2528
- NatureCityTrueCirc18.5 mgper 1 Softgel(s)DSLD:283374
- NutriCologyTocomin SupraBio Tocotrienols 100 mg6.5 mgper 1 Softgel(s)DSLD:258758
- NutriCologyTocomin SupraBio Tocotrienols 100 mg6.5 mgper 1 Softgel(s)DSLD:258759
- NutriCologyTocomin SupraBio Tocotrienols 200 mg13 mgper 1 Softgel(s)DSLD:258761
- NutriCologyTocomin SupraBio Tocotrienols 200 mg13 mgper 1 Softgel(s)DSLD:258780
- OL Olympian LabsVitamin E Complete5 mgper 1 Softgel(s)DSLD:326669
- Protocol For Life BalanceOrtho-EPalm · Plant Squalene (Form: Palm, from Tocomin(R))1.5 mgper 1 Softgel(s)DSLD:15039
- SolgarShark Liver Oil Complex 500 mg500 mgper 2 Softgel(s)DSLD:218681
- SuperSmartCoenzyme Q10 + Tocotrienols 300 mg6 mgper 2 Softgel(s)DSLD:250258
Label record: NIH Office of Dietary Supplements · CC0
Other names
5 names
Resolves to: squalene
- Also called
- (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene2,6,10,15,19,23-hexamethyltetracosa-2,6E,10E,14E,18E,22-hexaeneSpinaceneSupraene
- Systematic name
- (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene