Compound
Fe(II)-heme o
The cyclic tetrapyrrole anion that is ferroheme o protonated to pH 7.3.
Definition from ChEBI (CHEBI:60530), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C49H56FeN4O5
- Mass
- 836.855 g/mol
- Charge
- -2
- InChIKey
- FISPASSVCDRERW-ARQJTVBPSA-J
- SMILES
- C=CC1=C(C)C2=[N+]3C1=Cc1c(C)c(CCC(=O)[O-])c4[n]1[Fe-2]31[n]3c(c(C)c([C@@H](O)CC/C=C(C)CC/C=C(C)CCC=C(C)C)c3=C2)=CC2=[N+]1C(=C4)C(CCC(=O)[O-])=C2C
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: Fe(II)-heme o · Sources: Rhea
- Fe(II)-heme o is a substrate of COX10ProteinRhea RHEA:28070Inferred only
- Fe(II)-heme o is a substrate of COX15ProteinRhea RHEA:63388Inferred only
Reactions
6 reactions
(2E,6E)-farnesyl diphosphate+water+heme bdiphosphate(3-)+Fe(II)-heme o
Catalysed by COX10
Reaction pageLeft to rightBalancedEC 2.5.1.-, 2.5.1.141mitochondrial matrix
Human-GEM MAR20090CC BY 4.0Reference data
(2E,6E)-farnesyl diphosphate+water+heme bdiphosphate(3-)+Fe(II)-heme o
Catalysed by COX10
Reaction pageLeft to rightBalancedEC 2.5.1.-, 2.5.1.141cytosol
Human-GEM MAR20091CC BY 4.0Reference data
(2E,6E)-farnesyl diphosphate+water+heme bdiphosphate(3-)+Fe(II)-heme o
Catalysed by COX10
Reaction pageLeft to rightBalancedEC 2.5.1.-, 2.5.1.141nucleus
Human-GEM MAR20092CC BY 4.0Reference data
heme b+(2E,6E)-farnesyl diphosphate+waterFe(II)-heme o+diphosphate(3-)
Catalysed by COX10
Reaction pageDirection not assertedBalanced
Rhea RHEA:28070CC BY 4.0Reference data
Fe(II)-heme o+2A+waterFe(II)-heme a+2AH2
Catalysed by COX15
Reaction pageLeft to rightBalanced
Rhea RHEA:63388CC BY 4.0Reference data
Fe(II)-heme o+A+waterCHEBI:147291+AH2
Reaction pageDirection not assertedBalanced
Rhea RHEA:63392CC BY 4.0Reference data
Other names
2 names
Resolves to: Fe(II)-heme o
- Systematic name
- [3,3'-{7-ethenyl-12-[(1S,4E,8E)-1-hydroxy-5,9,13-trimethyltetradeca-4,8,12-trien-1-yl]-3,8,13,17-tetramethylporphyrin-2,18-diyl-kappa(4)N(21),N(22),N(23),N(24)}dipropanoato(4-)]iron[3,3'-{7-ethenyl-12-[(1S,4E,8E)-1-hydroxy-5,9,13-trimethyltetradeca-4,8,12-trien-1-yl]-3,8,13,17-tetramethylporphyrin-2,18-diyl-κ4N21,N22,N23,N24}dipropanoato(4−)]iron