trans-4-hydroxy-L-proline

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. transport of alanine and phenylalanine (cytosol to extracellular)

Catalysed by SLC1A4, SLC7A5inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 6 routes

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. 3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)

Catalysed by SLC1A4, KYNUinner side of the membrane, outer side of the membrane

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine

Catalysed by SLC1A4, AGXT2inner side of the membrane, outer side of the membrane

1. trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)
2. L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)

Catalysed by PRODH2, PRODHOne of 3 routes

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. gamma-glutamyltransferase (alanine)

Catalysed by SLC1A4, GGTLC3, GGT1, GGT5 and 3 moreinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by SLC1A4, MOCOSinner side of the membrane, outer side of the membrane

1. trans-4-hydroxy-L-proline(out) + L-threonine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-threonine(out) + Na(+)(in)
2. L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O

Catalysed by SLC1A4, YRDCinner side of the membrane, outer side of the membrane

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate

Catalysed by SLC1A4, AGXT2inner side of the membrane, outer side of the membrane

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. transport of alanine and tryptophan (cytosol to extracellular)
3. beta-carboline hydrolysis

Catalysed by SLC1A4, SLC7A5inner side of the membrane, outer side of the membrane, extracellular space, cytosol

1. trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
3. Carnitine O-Palmitoyltransferase

Catalysed by