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Proteins/UNIPROT:Q86U90
Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters (By similarity)..
Function from UniProtKB (Q86U90), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
57 statements
57 statements · 4 reference databases · Subject: YRDC · Sources: gene ontology, Hetionet, Reactome, Rhea
1 reaction
L-threonine+hydrogencarbonate+ATP(4-)L-threonylcarbamoyladenylate+diphosphate(3-)+water
Catalysed by YRDC
Reaction pageDirection not assertedBalanced
Rhea RHEA:36407CC BY 4.0Reference data
5 names
Resolves to: YRDC