4-maleylacetoacetic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

28 compounds within 3 steps: 1 in 1, 3 in 2, 24 in 3

One step

4-fumarylacetoacetateReach from here →
1. 4-Maleylacetoacetate cis-trans-isomerase
Catalysed by GSTZ1cytosol

Two steps

acetoacetateReach from here →
1. 4-Maleylacetoacetate cis-trans-isomerase
2. 4-fumarylacetoacetate fumarylhydrolase
Catalysed by GSTZ1, FAHcytosolOne of 2 routes
4-maleylacetoacetateReach from here →
1. 4-Maleylacetoacetate cis-trans-isomerase
2. 4-maleylacetoacetate = 4-fumarylacetoacetate
Catalysed by GSTZ1cytosol
fumaric acidReach from here →
1. 4-Maleylacetoacetate cis-trans-isomerase
2. 4-fumarylacetoacetate fumarylhydrolase
Catalysed by GSTZ1, FAHcytosolOne of 2 routes

Three steps

, FAH

, SLC16A4

, SLC16A5

cytosol, extracellular space

One of 2 routes

a quinoneReach from here →

Catalysed by GSTZ1, FAH, SDHBcytosol

CHEBI:15345Reach from here →

Catalysed by GSTZ1, FAH, AACScytosolOne of 3 routes

acetoneReach from here →

Catalysed by GSTZ1, FAHcytosol, mitochondrial matrix

pyruvateReach from here →

Catalysed by GSTZ1, FAHcytosol, mitochondrial matrixOne of 4 routes

all-trans-retinoic acidReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

(S)-malateReach from here →

Catalysed by GSTZ1, FAH, FHcytosolOne of 5 routes

sulfateReach from here →

Catalysed by GSTZ1, FAH, SLC25A10cytosol, mitochondrial matrixOne of 2 routes

ubiquinonesReach from here →

Catalysed by GSTZ1, FAH, SDHD, SDHB and 2 morecytosol, mitochondrial matrix

3-fumarylpyruvateReach from here →

Catalysed by GSTZ1, FAH, FAHD1cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by GSTZ1, FAH, BDH1, BDH2cytosol, mitochondrial matrixOne of 4 routes

sulfiteReach from here →

Catalysed by GSTZ1, FAH, SLC25A10cytosol, mitochondrial matrixOne of 2 routes

acetateReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

thiosulfateReach from here →

Catalysed by GSTZ1, FAH, SLC25A10cytosol, mitochondrial matrixOne of 2 routes

(S)-lactic acidReach from here →

Catalysed by GSTZ1, FAH, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

(3S)-3-hydroxy-3-methylglutaryl-CoAReach from here →

Catalysed by GSTZ1, FAH, HMGCL, HMGCLL1cytosol

acetoacetyl-CoAReach from here →

Catalysed by GSTZ1, FAH, AACScytosolOne of 2 routes

2-(N(omega)-L-arginino)succinateReach from here →

Catalysed by GSTZ1, FAH, ASLcytosolOne of 2 routes

N(6)-(1,2-dicarboxyethyl)-AMPReach from here →

Catalysed by GSTZ1, FAH, ADSL, TNRC6BcytosolOne of 2 routes

(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateReach from here →

Catalysed by GSTZ1, FAH, ADSLcytosolOne of 2 routes