Compound
choloyl-CoA
An acyl-CoA(4−) that is the tetraanion of choloyl-CoA, arising from deprotonation of phosphate and diphosphate functions.
Definition from ChEBI (CHEBI:57373), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C45H70N7O20P3S
- Mass
- 1154.073 g/mol
- Charge
- -4
- InChIKey
- ZKWNOTQHFKYUNU-JGCIYWTLSA-J
- SMILES
- [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@@]3(C)[C@@]([H])(CC[C@]3([H])[C@]([H])(C)CCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3OP(=O)([O-])[O-])[C@]1([H])[C@H](O)C2
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: choloyl-CoA · Sources: Rhea
- cholate is converted to choloyl-CoACompoundRhea RHEA:23532Inferred only
- choloyl-CoA is converted to cholateCompoundRhea RHEA:14541Inferred only
- choloyl-CoA is converted to S-choloyl-4'-phosphopantetheineCompoundRhea RHEA:50036Inferred only
- choloyl-CoA is a substrate of ACOT8ProteinRhea RHEA:14541Inferred only
- choloyl-CoA is a substrate of BAATProteinRhea RHEA:14541Inferred only
- choloyl-CoA is a substrate of BAATProteinRhea RHEA:14001Inferred only
- choloyl-CoA is a substrate of BAATProteinRhea RHEA:47100Inferred only
- choloyl-CoA is a substrate of NUDT19ProteinRhea RHEA:50036Inferred only
- choloyl-CoA is a substrate of NUDT7ProteinRhea RHEA:50036Inferred only
Reactions
10 reactions
choloyl-CoA+glycineglycocholate+coenzyme A(4-)+hydron
Catalysed by BAAT
Reaction pageLeft to rightBalanced
Rhea RHEA:14001CC BY 4.0Reference data
choloyl-CoA+watercholate+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:14541CC BY 4.0Reference data
choloyl-CoA+propanoyl-CoA3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA+coenzyme A(4-)
Catalysed by SCP2
Reaction pageRight to leftBalanced
Rhea RHEA:16865CC BY 4.0Reference data
cholate+ATP(4-)+coenzyme A(4-)choloyl-CoA+AMP+diphosphate(3-)
Catalysed by SLC27A5
Reaction pageLeft to rightBalanced
Rhea RHEA:23532CC BY 4.0Reference data
choloyl-CoA+taurinetaurocholate+coenzyme A(4-)+hydron
Catalysed by BAAT
Reaction pageLeft to rightBalanced
Rhea RHEA:47100CC BY 4.0Reference data
lithocholoyl-CoA+cholatecholoyl-CoA+lithocholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:49432CC BY 4.0Reference data
deoxycholoyl-CoA+cholatecholoyl-CoA+deoxycholate
Reaction pageDirection not assertedBalanced
Rhea RHEA:49436CC BY 4.0Reference data
choloyl-CoA+waterS-choloyl-4'-phosphopantetheine+adenosine 3',5'-bisphosphate+2hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:50036CC BY 4.0Reference data
choloyl-CoA+NAD(1-)CHEBI:136700+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:52588CC BY 4.0Reference data
CHEBI:137664+cholateCHEBI:137662+choloyl-CoA
Reaction pageDirection not assertedBalanced
Rhea RHEA:53756CC BY 4.0Reference data
Other names
9 names
Resolves to: choloyl-CoA
- Also called
- choloyl-CoA tetraanioncholoyl-coenzyme A(4-)choloyl-coenzyme A(4−)cholyl-CoA(4-)cholyl-CoA(4−)cholyl-coenzyme A(4-)cholyl-coenzyme A(4−)
- Systematic name
- 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)sulfanyl]ethyl}amino)propyl]amino}butyl] diphosphate}3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3α,7α,12α-trihydroxy-5β-cholan-24-oyl)sulfanyl]ethyl}amino)propyl]amino}butyl] diphosphate}