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Proteins/UNIPROT:Q13202
Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues..
Function from UniProtKB (Q13202), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
36 statements
36 statements · 3 reference databases · Subject: DUSP8 · Sources: Hetionet, Reactome, WikiPathways
3 reactions
3 names
Resolves to: DUSP8
O-phospho-L-seryl-[protein]+waterL-seryl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 61 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20629CC BY 4.0Reference data
O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47004CC BY 4.0Reference data