a sterol ester

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

145 compounds within 3 steps: 3 in 1, 31 in 2, 111 in 3

Three steps

phosphatidic acidReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
Catalysed by LCAT, LPGAT1, AGPAT2, LCLAT1 and 7 moremitochondrial matrixOne of 9 routes
CHEBI:16436Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
3. ceramide cholinephosphotransferase (CDP-choline)
Catalysed by LCAT, SGMS1, SGMS2endoplasmic reticulum
1-phosphatidyl-1D-myo-inositolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phosphocholine(out)
3. ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase
Catalysed by LCAT, OSBPL3, PTPRQ, INPPL1 and 11 moreinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes
sn-glycerol 3-phosphocholineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)
Catalysed by CEL, LIPA, LIPN, LCAT and 11 moreOne of 6 routes
1-acyl-sn-glycerol 3-phosphateReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)
3. ATP:acylglycerol 3-phosphotransferase
Catalysed by CEL, LIPA, LIPN, LIPE and 1 morecytosolOne of 7 routes
a cholesterol esterReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an acyl-CoA + cholesterol = a cholesterol ester + CoA
Catalysed by LCAT, LPGAT1, SOAT2, SOAT1
all-trans-retinolReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)
3. carboxylesterase (retinyl-ester)
Catalysed by CEL, LIPA, LIPN, RPE65 and 19 morecytosolOne of 2 routes
a 2-acylglycerolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)
3. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
Catalysed by LCAT, SMPD1, DAGLB, ABHD11 and 1 more
1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. Acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase
Catalysed by LCAT, LPGAT1, LPCAT4, LPCAT3 and 2 morecytosol
AH2Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)
3. choline + A = betaine aldehyde + AH2
Catalysed by LCAT, PLD2, PLD1, ENPP2 and 1 more
glycerolReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)
3. a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)
Catalysed by CEL, LIPA, LIPN, LIPEOne of 3 routes
a diacylglycerolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a triacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
3. a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)
Catalysed by LCAT, TMEM68, DDHD2, LPL and 17 moreOne of 2 routes
CHEBI:18132Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)
3. ATP:choline phosphotransferase
Catalysed by LCAT, PLD2, PLD1, ENPP2 and 2 morecytosolOne of 5 routes
11-cis-retinyl esterReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. 11-cis-retinol + a fatty acyl-CoA = 11-cis-retinyl ester + CoA
Catalysed by CEL, LIPA, LIPN, ACSL3 and 1 more
13-cis-retinyl esterReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. 13-cis-retinol + a fatty acyl-CoA = 13-cis-retinyl ester + CoA
Catalysed by CEL, LIPA, LIPN, ACSL3 and 1 more
9-cis-retinyl esterReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. 9-cis-retinol + a fatty acyl-CoA = 9-cis-retinyl ester + CoA
Catalysed by CEL, LIPA, LIPN, ACSL3 and 1 more
(11Z)-docosenoyl-CoA(4-)Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
(7Z)-tetradecenoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
a long-chain alcohol wax esterReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. a long chain fatty alcohol + a fatty acyl-CoA = a long-chain alcohol wax ester + CoA
Catalysed by CEL, LIPA, LIPN, ACSL3 and 2 more
elaidic acidReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
chlorine(.)Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)
3. transport of chloride and choline (cytosol to extracellular)
Catalysed by LCAT, PLD2, PLD1, ENPP2 and 1 moreextracellular space, cytosol
a 1-O-alkyl-sn-glycero-3-phosphocholineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol = a 1-O-alkyl-sn-glycero-3-phosphocholine + a triacylglycerol
Catalysed by LCAT, PLA2G15, TMEM68
an N-acylsphinganineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. a fatty acyl-CoA + sphinganine = an N-acylsphinganine + CoA + H(+)
Catalysed by CEL, LIPA, LIPN, ACSL3 and 4 moreOne of 4 routes
an N-acyl-(4R)-4-hydroxysphinganineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)
3. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LCAT, SMPD1, SGMS1, SGMS2One of 2 routes
an acylcholineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)
3. an acylcholine + H2O = a carboxylate + choline + H(+)
Catalysed by LCAT, PLD2, PLD1, ENPP2 and 1 more
fatty acidReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)
3. 1-acylglycerol acylhydrolase
Catalysed by CEL, LIPA, LIPN, LIPE and 3 morecytosolOne of 19 routes
a 1-acylglycerolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1,3-diacylglycerol + H2O = a 1-acylglycerol + a fatty acid + H(+)
Catalysed by LCAT, PLA2G15, DDHD2, LIPAOne of 2 routes
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. Acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase
Catalysed by LCAT, LPGAT1, LPCAT4, LPCAT3 and 2 morecytosol
an N-acylsphing-4-enineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
3. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)
Catalysed by CEL, LIPA, LIPN, ACSL3 and 6 moreOne of 11 routes
an N-acylethanolamineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine + H(+)
3. an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)
Catalysed by LCAT, PLA2G4E, PLAAT5, PLAAT2 and 1 more
(6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
dodecanoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
eicosanoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
(9Z,12Z)-octadecadienoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
tetradecanoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
octadecanoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
a 1-acylglycerone 3-phosphateReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA
Catalysed by LCAT, LPGAT1, GNPAT
an N-acylglycineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by LCAT, LPGAT1, GLYATL3, GLYAT and 1 more
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine
Catalysed by CEL, LIPA, LIPN, LCAT and 1 moreOne of 5 routes
a 1-acyl-sn-glycero-3-phosphateReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)
Catalysed by CEL, LIPA, LIPN, LCAT and 1 moreOne of 3 routes
a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by CEL, LIPA, LIPN, LCAT and 1 more
a CDP-1,2-diacyl-sn-glycerolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)
3. a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate
Catalysed by LCAT, PLD2, PLD1, ENPP2 and 3 moreOne of 2 routes
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phosphocholine(out)
3. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)
Catalysed by LCAT, OSBPL3, PIP5K1B, PIP5K1C and 1 moreinner side of the membrane, outer side of the membrane
CDP-cholineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)
3. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
Catalysed by LCAT, SMPD1, PCYT1A, PCYT1BOne of 2 routes
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by CEL, LIPA, LIPN, LCAT and 1 more
(9Z)-hexadecenoyl-CoAReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
CHEBI:63544Reach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by LCAT, LPGAT1cytosol
a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
Catalysed by LCAT, PTDSS1, PLA2G15
a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a sterol ester + H2O = a sterol + a fatty acid + H(+)
2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine
Catalysed by CEL, LIPA, LIPN, LCAT and 1 moreOne of 5 routes
a triacyl-sn-glycerolReach from here →
1. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
Catalysed by LCAT, LPGAT1, DGAT1, MOGAT2 and 4 moreOne of 2 routes