Compound
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine
An alkyl,acyl-sn-glycero-3-phosphocholine in which unspecified alkyl and acyl groups are located at positions 1 and 2 respectively.
Definition from ChEBI (CHEBI:36702), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C9H18NO7PR2
- Mass
- 283.216 g/mol
- Charge
- 0
- SMILES
- *C(=O)O[C@H](CO[1*])COP(=O)([O-])OCC[N+](C)(C)C
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
26 entities
26 entities reached.
0 reported hops26 assembled from the scaffold
- PLA2G4AProteinUNIPROT:P47712substrate ofInferred only120 paths60 endpoints
- PLA2G6ProteinUNIPROT:O60733substrate ofInferred only46 paths23 endpoints
- PLA2G2AProteinUNIPROT:P14555substrate ofInferred only37 paths37 endpoints
- PLA2G4FProteinUNIPROT:Q68DD2substrate ofInferred only26 paths13 endpoints
- PLIN1ProteinUNIPROT:O60240substrate ofInferred only25 paths25 endpoints
- PLA2G4CProteinUNIPROT:Q9UP65substrate ofInferred only24 paths12 endpoints
- PLA2G1BProteinUNIPROT:P04054substrate ofInferred only22 paths22 endpoints
- PLA2G4BProteinUNIPROT:P0C869substrate ofInferred only20 paths20 endpoints
- PLB1ProteinUNIPROT:Q6P1J6substrate ofInferred only20 paths10 endpoints
- PLIN2ProteinUNIPROT:Q99541substrate ofInferred only20 paths20 endpoints
- PLIN3ProteinUNIPROT:O60664substrate ofInferred only19 paths19 endpoints
- PLA2G5ProteinUNIPROT:P39877substrate ofInferred only17 paths17 endpoints
Show the remaining 14
- PLA2G10ProteinUNIPROT:O15496substrate ofInferred only14 paths14 endpoints
- PLA2G4DProteinUNIPROT:Q86XP0substrate ofInferred only14 paths14 endpoints
- PLA2G12AProteinUNIPROT:Q9BZM1substrate ofInferred only14 paths14 endpoints
- PLA2G4EProteinUNIPROT:Q3MJ16substrate ofInferred only12 paths12 endpoints
- PLA2G2DProteinUNIPROT:Q9UNK4substrate ofInferred only12 paths12 endpoints
- PLA2G2FProteinUNIPROT:Q9BZM2substrate ofInferred only11 paths11 endpoints
- PLA2G2EProteinUNIPROT:Q9NZK7substrate ofInferred only11 paths11 endpoints
- PLAAT3ProteinUNIPROT:P53816substrate ofInferred only11 paths11 endpoints
- PLA2G3ProteinUNIPROT:Q9NZ20substrate ofInferred only9 paths9 endpoints
- PLIN4ProteinUNIPROT:Q96Q06substrate ofInferred only6 paths6 endpoints
- BSCL2ProteinUNIPROT:Q96G97substrate ofInferred only5 paths5 endpoints
- FITM2ProteinUNIPROT:Q8N6M3substrate ofInferred only3 paths3 endpoints
- FITM1ProteinUNIPROT:A5D6W6substrate ofInferred only3 paths3 endpoints
- PAFAH2ProteinUNIPROT:Q99487substrate ofInferred only2 paths2 endpoints
What the reference databases state
Statements
32 statements
32 statements · 2 reference databases · Subject: a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine · Sources: Human-GEM, Rhea
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of BSCL2ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of FITM1ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of FITM2ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PAFAH2ProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G10ProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G12AProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G1BProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2AProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2DProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2EProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2FProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G3ProteinHuman-GEM MAR07615Inferred only
Show the remaining 20
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4AProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4AProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4BProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4DProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4EProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4FProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4FProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G5ProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G6ProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLA2G6ProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLAAT3ProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLB1ProteinRhea RHEA:36231Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLB1ProteinHuman-GEM MAR07615Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLIN1ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLIN2ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLIN3ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of PLIN4ProteinHuman-GEM MAR00031Inferred only
- a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine is a substrate of TMEM68ProteinRhea RHEA:77759Inferred only
Reactions
12 reactions
0.19a 1,2-diacyl-sn-glycerol+0.0014MAM00511c+0.0024a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+0.00061-O-acyl-sn-glycero-3-phosphocholine(1+)+0.005CHEBI:1307929+0.34a cholesterol ester+0.00081-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine+0.00921,2-diacyl-sn-glycero-3-phosphocholine(1+)+0.0034phosphatidylethanolamine+0.00161-phosphatidyl-1D-myo-inositol+0.0002phosphatidyl-L-serine+0.0004a sphingomyelin+0.44a triacylglycerol+0.005fatty acidMAM02392c
Catalysed by PLIN3 or FITM1 or PLIN2 or PLIN1 or PLIN4 or BSCL2 or FITM2
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00031CC BY 4.0Reference data
1-O-alkyl-2-acyl-sn-glycerol+CHEBI:16436a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+cytidine 5'-monophosphate+proton
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.2cytosol
Human-GEM MAR07600CC BY 4.0Reference data
MAM00549c+an acyl-CoAa 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+CHEBI:1146900
Catalysed by LPCAT2 or LPCAT3 or LPCAT1 or LPCAT4
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.23cytosol
Human-GEM MAR07614CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+waterMAM00549c+proton+fatty acid
Catalysed by PLA2G10 or PLA2G3 or PLA2G4C or PLA2G4A or PLA2G2D or PLA2G12A or PLA2G5 or PLA2G2F or PLA2G4D or PLB1 or PLA2G4F or PLA2G1B and 6 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.4cytosol
Human-GEM MAR07615CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+waterMAM00516c+proton+fatty acid
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR08522CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholinea 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20972CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+an acyl-CoAa 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23992CC BY 4.0Reference data
1-O-alkyl-2-acyl-sn-glycerol+CDP-cholinea 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+CMP+hydron
Catalysed by CEPT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36179CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G6 or PLA2G4A or PLA2G4F or PLB1 or PAFAH2 or PLA2G4C
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36231CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+sphing-4-eninea 1-O-alkyl-sn-glycero-3-phosphocholine+an N-acylsphing-4-enine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44660CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolaminea 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44684CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+a 1,2-diacylglycerola 1-O-alkyl-sn-glycero-3-phosphocholine+a triacylglycerol
Catalysed by TMEM68
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:77759CC BY 4.0Reference data
Other names
8 names
Resolves to: a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine
- Also called
- 1-alkyl-2-acyl-sn-glycero-3-phosphocholine1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine1-Organyl-2-acyl-sn-glycero-3-phosphocholine1-Radyl-2-acyl-sn-glycero-3-phosphocholine2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaines2-acyl-1-alkyl-sn-glycero-3-phosphocholinesPC-OPC(O-)