Compound

a 1-acylglycerol

Glycerol esterified with a single acyl (fatty acids) chain.

Definition from MeSH (D050178), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:35759ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound
Formula: C4H7O4R
Mass: 119.096 g/mol
Charge: 0
SMILES: *C(=O)OCC(O)CO
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

10 entities

10 entities reached.

0 reported hops10 assembled from the scaffold

What the reference databases state

Statements

19 statements

19 statements · 1 reference database · Subject: a 1-acylglycerol · Sources: Rhea

Order

a 1-acylglycerol is a substrate of ABHD16BProteinRhea RHEA:34019Inferred only
a 1-acylglycerol is a substrate of ABHD6ProteinRhea RHEA:34019Inferred only
a 1-acylglycerol is a substrate of AWAT2ProteinRhea RHEA:39943Inferred only
a 1-acylglycerol is a substrate of DDHD2ProteinRhea RHEA:34019Inferred only
a 1-acylglycerol is a substrate of LPGAT1ProteinRhea RHEA:65100Inferred only
a 1-acylglycerol is a substrate of MGLLProteinRhea RHEA:34019Inferred only
a 1-acylglycerol is a substrate of MOGAT1ProteinRhea RHEA:77571Inferred only
a 1-acylglycerol is a substrate of MOGAT1ProteinRhea RHEA:39943Inferred only
a 1-acylglycerol is a substrate of MOGAT2ProteinRhea RHEA:77571Inferred only
a 1-acylglycerol is a substrate of MOGAT2ProteinRhea RHEA:39943Inferred only
a 1-acylglycerol is a substrate of PNPLA2ProteinRhea RHEA:44432Inferred only
a 1-acylglycerol is a substrate of PNPLA2ProteinRhea RHEA:44436Inferred only

Show the remaining 7

a 1-acylglycerol is a substrate of PNPLA2ProteinRhea RHEA:44440Inferred only
a 1-acylglycerol is a substrate of PNPLA3ProteinRhea RHEA:44432Inferred only
a 1-acylglycerol is a substrate of PNPLA3ProteinRhea RHEA:44440Inferred only
a 1-acylglycerol is a substrate of PNPLA3ProteinRhea RHEA:44436Inferred only
a 1-acylglycerol is a substrate of PNPLA4ProteinRhea RHEA:44440Inferred only
a 1-acylglycerol is a substrate of PNPLA4ProteinRhea RHEA:44432Inferred only
a 1-acylglycerol is a substrate of PNPLA4ProteinRhea RHEA:44436Inferred only

Reactions

10 reactions

a 1-acylglycerol+waterglycerol+a fatty acid+hydron
Catalysed by DDHD2 or MGLL or ABHD6 or ABHD16B
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:34019CC BY 4.0Reference data
a 1-acylglycerol+an acyl-CoAa 1,2-diacylglycerol+coenzyme A(4-)
Catalysed by MOGAT2 or AWAT2 or MOGAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39943CC BY 4.0Reference data
glycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea 1-acylglycerol+a 1-acyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44428CC BY 4.0Reference data
2a 1-acylglycerola 1,2-diacylglycerol+glycerol
Catalysed by PNPLA4 or PNPLA2 or PNPLA3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44432CC BY 4.0Reference data
a 1-acylglycerol+a 1,2-diacylglycerola triacylglycerol+glycerol
Catalysed by PNPLA4 or PNPLA2 or PNPLA3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44436CC BY 4.0Reference data
a 1-acylglycerol+a 1,3-diacylglycerola triacylglycerol+glycerol
Catalysed by PNPLA4 or PNPLA2 or PNPLA3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44440CC BY 4.0Reference data
a 1,2-diacylglycerol+watera 1-acylglycerol+a fatty acid+hydron
Catalysed by LIPA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44712CC BY 4.0Reference data
a 1-acylglycerol+hexadecanoyl-CoAan hexadecanoyl-acylglycerol+coenzyme A(4-)
Catalysed by LPGAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:65100CC BY 4.0Reference data
a 1-acylglycerol+an acyl-CoAa 1,3-diacylglycerol+coenzyme A(4-)
Catalysed by MOGAT2 or MOGAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:77571CC BY 4.0Reference data
a 1,3-diacylglycerol+watera 1-acylglycerol+a fatty acid+hydron
Catalysed by DDHD2 or LIPA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:78019CC BY 4.0Reference data

Other names

10 names

Resolves to: a 1-acylglycerol

Also called: 1-Acylglycerol1-Monoacylglycerol1-monoacylglycerols1(3)-acylglycerolGlycerideMAGMGMonoacylglycerolMonoglyceride
Systematic name: 1-monoglycerides