phosphatidylethanolamine

Three steps

• an N-acyl-sphinga-4E,14Z-dienineReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
  3. an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyl-sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O

  Catalysed by PIGF, PIGG, SGMS1, SGMS2 and 1 moreendoplasmic reticulum

• a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
  3. a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

  Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulum

• a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
  3. a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

  Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulum

• a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
  3. a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

  Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulum

• a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
  3. a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

  Catalysed by PIGF, PIGG, SELENOI, CEPT1endoplasmic reticulum

• 8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. arachidonate to 8-peroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate conversion

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 14 morecytosol, extracellular spaceOne of 2 routes

• 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerolReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O = 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serineReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 16 morecytosol, extracellular space

• (7Z)-octadecenoyl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosolOne of 3 routes

• CHEBI:15345Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. Acetoacetate:CoA ligase (AMP-forming)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 4 moreendoplasmic reticulum, cytosolOne of 2 routes

• acetylcholineReach from here →
  1. Phosphatidylethanolamine N-Methyltransferase
  2. phosphatidylserine synthase (PC-LD pool)
  3. Acetyl-CoA:choline O-acetyltransferase

  Catalysed by PEMT, PTDSS1, CHATmitochondrial matrix, cytosolOne of 3 routes

• CHEBI:15380Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. 5-aminolevulinate synthase (2-amino-3-oxoadipate)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 5 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 8 routes

• CHEBI:15477Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. glycine N-acyltransferase (2-methylbutyryl-CoA)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

• 2-methylcrotonoyl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. Production of Tiglylcarnitine

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 5 moreendoplasmic reticulum, cytosolOne of 2 routes

• isobutyryl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

• 3-methylbut-2-enoyl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. glycine-N-acyltransferase (3-methylcrotonoylglycine)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 4 moreendoplasmic reticulum, cytosol, mitochondrial matrix

• isovaleryl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. glycine N-acyltransferase (isovalerylglycine)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

• arachidonoyl-CoAReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. Arachidonate:CoA ligase (AMP-forming)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 14 routes

• CHEBI:15519Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. propanoyl-CoA C-acyltransferase

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosol, peroxisomeOne of 2 routes

• palmitoyl-CoAReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. Palmitate:CoA ligase (AMP-forming)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 14 routes

• oleoyl-CoAReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. long-chain-fatty-acid-CoA ligase (oleate)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 14 routes

• phenylacetyl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. Phenylacetate:CoA ligase

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 3 moreendoplasmic reticulum, cytosolOne of 3 routes

• propionyl-CoAReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. Propanoate:CoA ligase (AMP-forming)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosolOne of 43 routes

• (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• (11S)-hydroperoxy-(4Z,7Z,9E,13Z,16Z,19Z)-docosahexaenoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (11S)-hydroperoxy-(4Z,7Z,9E,13Z,16Z,19Z)-docosahexaenoate

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 12(S)-HPETEReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. arachidonate:oxygen 12-oxidoreductase

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular spaceOne of 4 routes

• 15(S)-HPETEReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. arachidonate:oxygen 15-oxidoreductase

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 16 morecytosol, extracellular spaceOne of 4 routes

• 5(S)-HPETEReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. Arachidonate:oxygen 5-oxidoreductase

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• a 1-hexadecanoyl-2-acylglycerolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
  3. a 2-acylglycerol + hexadecanoyl-CoA = a 1-hexadecanoyl-2-acylglycerol + CoA

  Catalysed by PIGF, PIGG, DAGLB, ABHD11 and 2 moreendoplasmic reticulum

• CHEBI:15650Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. N-acetyl-LTE4 to leukotriene E4 conversion

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 35 moreendoplasmic reticulum, cytosolOne of 2 routes

• betaine aldehydeReach from here →
  1. Phosphatidylethanolamine N-Methyltransferase
  2. phosphatidylserine synthase (PC-LD pool)
  3. choline dehydrogenase (choline)

  Catalysed by PEMT, PTDSS1, CHDHmitochondrial matrix, cytosolOne of 3 routes

• CHEBI:15727Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 4 moreendoplasmic reticulum, cytosol

• CHEBI:15746Reach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. diamine N-acetyltransferase (N1-acetylspermine)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 5 moreendoplasmic reticulum, cytosolOne of 2 routes

• cholesterolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
  3. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine

  Catalysed by PIGF, PIGG, SGMS1, SGMS2 and 2 moreendoplasmic reticulumOne of 4 routes

• CHEBI:16132Reach from here →
  1. L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
  2. ethanolamine ammonia-lyase (acetaldehyde-forming)
  3. deoxyribose-phosphate aldolase

  Catalysed by PTDSS2, DERAcytosol

• 11-cis-retinyl hexadecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. 11-peroxy-docosahexaenoate to DHA conversion

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 14 morecytosol, extracellular spaceOne of 3 routes

• 11-cis-retinolReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. Palmitoyl-CoA:retinol O-acyltransferase

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosolOne of 3 routes

• CHEBI:16436Reach from here →
  1. Phosphatidylethanolamine N-Methyltransferase
  2. ceramide:phosphatidylcholine cholinephosphotransferase
  3. ceramide cholinephosphotransferase (CDP-choline)

  Catalysed by PEMT, SGMS1, SGMS2mitochondrial matrix, Golgi apparatus, endoplasmic reticulum

• oxaloacetateReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
  3. ATP citrate lyase (citrate)

  Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 4 moreendoplasmic reticulum, cytosol

• CHEBI:16566Reach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. N-acylsphingosine amidohydrolase
  3. N-acylsphingosine amidohydrolase

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 19 morecytosol

• 8-hydroxydodecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 8-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 10-hydroxydodecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 9-hydroxydodecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 9-hydroxytetradecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 10-hydroxytetradecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 12-hydroxytetradecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 12-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• 11-hydroxytetradecanoateReach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space

• CHEBI:16856Reach from here →
  1. phosphatidylethanolamine 2-acylhydrolase
  2. (10Z)-heptadecenoic acid formation
  3. transport of arachidonate and GSH (cytosol to extracellular)

  Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 14 morecytosol, extracellular spaceOne of 2 routes

• sn-glycerol 3-phosphocholineReach from here →
  1. Phosphatidylethanolamine N-Methyltransferase
  2. phosphatidylcholine 2-acylhydrolase
  3. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase

  Catalysed by PEMT, PLA2G10, PLA2G6, PLA2G1B and 23 moremitochondrial matrix, endoplasmic reticulum, cytosol

• 1-acyl-sn-glycerol 3-phosphateReach from here →
  1. M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
  2. 1,2-diacyl-sn-glycerol acylhydrolase
  3. ATP:acylglycerol 3-phosphotransferase

  Catalysed by PIGF, PIGG, LIPF, LIPC and 14 moreendoplasmic reticulum, extracellular space, cytosolOne of 6 routes