3-oxooctadecanoyl-CoA

1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)

Catalysed by ACAA1, MYO5BperoxisomeOne of 2 routes

1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA

Catalysed by SCP2, HADHB

1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
2. Palmitoyl-CoA hydrolase

Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 3 moreperoxisome, cytosolOne of 17 routes

1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
2. hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by SCP2, HADHB, NUDT19,